Sentences with phrase «coactivator pgc»

When fastening to the PPAR receptor, it was discovered that Cardarine recruits the coactivator PGC - 1 a enzyme that increases genes appearance in the energy expenditure.

The expression of mRNA for factors involved in promoting mitochondrial biogenesis, including the transcription factor Ppard, the PPARδ coactivator Pgc - 1α, and citrate synthase was greater in gastrocnemius muscles from IL - 15Rα — KO relative to B6129 control (Figure 5C); however, levels of these genes were unchanged in spleen and kidney (data not shown).

These differences suggest that adapting to exercise involves many processes, but scientists have observed that one gene in particular, peroxisome proliferator - activated receptor - gamma coactivator PGC - 1α, controls many of them.

Not exact matches

Among the other genes she says play a role in thoroughbred performance are peroxisome proliferator - activated receptor - γ coactivator - 1 alpha (PGC - 1α), which is involved in skeletal muscle adaptation to exercise; pyruvate dehydrogenase kinase, isozyme 4 (PDK4), involved in glucose regulation, expression of which increased almost fourfold after sprints; and cytochrome c oxidase subunit 4 isoform 2 (COX 4I2), involved in respiration.

The findings in a recent issue of Cell demonstrate how PGC - 1a1, a transcriptional coactivator induced in skeletal muscle by exercise and endurance, protects the brain from depression.

FNDC5 expression was shown to correlate with peroxisome proliferator - activated receptor gamma coactivator 1 - alpha (PGC - 1α) expression levels in various developmental stages and tissues, including neurons.