Sentences with phrase «coactivators such»
However, it is unclear whether this enhanced interaction selectively facilitates transcription of specific p53 target genes, including sestrins, or whether p53 serine18 phosphorylation also regulates specific target genes by altering interactions of p53 with other coactivators such as chromatin modifying enzymes.
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GT198, which is also a coactivator of receptors for steroid hormones such as estrogen, is normally regulated by estrogen, Ko said.