Blood transfusions may be appropriate in dogs that have severe bleeding disorders associated with clotting and
coagulation abnormalities caused by liver disease.
Can not be given if platelet counts are low prior to treatment as
coagulation abnormalities could result.
Coagulation abnormalities and thrombocytopenia, including acute severe thrombocytopenia, have been observed after administration of some antisense oligonucleotides.
Because of the risk of thrombocytopenia and
coagulation abnormalities from SPINRAZA, patients may be at increased risk of bleeding complications.
Coagulation abnormalities and thrombocytopenia, including acute severe thrombocytopenia, have been observed after administration of some ASOs.
Not exact matches
The increased production of PAI - 1 and factor VII has been implicated in the development of
coagulation and fibrinolytic
abnormalities characteristic of obesity (28, 70).
In those with systemic
abnormalities, monitoring should be more aggressive and may include vital signs, weight, haematocrit, total protein, fl uid intake and output, blood pressure (central venous and arterial), electrolytes and glucose, acidbase status, platelets and
coagulation status.
Treatment - related findings included abnormal feces, effects on
coagulation, retinal changes, neurological
abnormalities, ECG changes, gross pathology changes and organ weight changes.
When a mutation or
abnormality occurs in these genes, it can disrupt the
coagulation process, preventing blood clotting and resulting in uncontrolled bleeding.
A few dogs develop chronic kidney disease (pyelonephritis), glaucoma or circulatory
abnormalities (vasculitis, disseminated intravascular
coagulation).