Basset hounds are in general healthy, but they are prone to some genetic diseases, such as von Willebrands (a bleeding disorder), Thrombopathia, (a blood
coagulation disorder), glaucoma (increased pressure in the eye leading to blindness), or disk rupture and other spinal problems.
* Warning: If you are allergic to shellfish, have a blood
coagulation disorder, or are taking anticoagulants such as Warfarin (Coumadin), consult a health care professional prior to use.
Use cautiously with high VLDL cholesterol, hypertriglyceridemia, or with a history of low blood pressure,
coagulation disorders, potential for mania, or epilepsy.
Areas of special interest include immunologic infertility, immunodeficiency,
coagulation disorders and tick - borne diseases.
The Biobank offers these DNA resources to scientists from all parts of the University, who can then use them to explore linkages between genes and specific feline diseases like diabetes, hypertrophic cardiomyopathy,
coagulation disorders, arthritis, kidney disease, obesity, dental disease, and lymphoma.
Surgery for patients with conditions requiring specialized anesthesia or analgesia, patients with
coagulation disorders, and patients with significant concurrent diseases
His clinical interests are critical care medicine, pain management in the ICU, long term ventilation, and
coagulation disorders.
Not exact matches
Transgenic mice overexpressing arginase 1 in monocytic cell lineage are affected by lympho - myeloproliferative
disorders and disseminated intravascular
coagulation.
• Patients must have adequate
coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding
disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study
Inclusion Criteria: • Availability of tumor tissue for mesothelin expression testing • Histologically - confirmed, mesothelin - expressing metastatic or advanced non-metastatic disease (tumour type specific inclusion criteria) • At least one measurable lesion according to either Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or International Thymic Malignancy Interest Group (ITMIG) modified RECIST 1.1 as applicable • Adequate bone marrow, liver, renal and
coagulation function • Left ventricular ejection fraction (LVEF) ≥ 50 % of the lower limit of normal (LLN) according to local institutional ranges • Eastern Cooperative Oncology Group (ECOG) 0 or 1 Exclusion Criteria: • More than one prior anti - tubulin / microtubule agent • Corneal epitheliopathy or any eye
disorder that may predispose the patients to this condition • Symptomatic Central nervous system (CNS) metastases and / or carcinomatous meningitis • Contraindication to both CT and MRI contrast agents • Active hepatitis B or C infection • Pregnant or breast - feeding patients • Tumor type specific exclusion criteria
The Hematology training focuses on
coagulation, hematologic malignancies, anemias, hemoglobinopathies, and qualitative and quantitative
disorders of leukocytes and platelets.
When this breakdown happens, the immune system responds by releasing products that cause an inflammatory reaction, activating abnormal clotting in the mother's lungs and blood vessels that can result in a serious blood - clotting
disorder known as disseminated intravascular
coagulation.
Those with bleeding
disorders or an upcoming surgery should not use or consume allspice, since its eugenol content can inhibit proper
coagulation.
Hemophilia A: a blood clotting
disorder due to deficiency of
coagulation factor VIII (this is the most common type of hemophilia in dogs).
In serious cases this can cause a bleeding
disorder called disseminated intravascular
coagulation (DIC).
Hemophilia A is a deficiency of
coagulation factor VIII, and is the most common inherited clotting
disorder in dogs.
The blood
disorder that most commonly accompanies the presence of hemangiosarcoma tumors is disseminated intravascular
coagulation (DIC).
Blood transfusions may be appropriate in dogs that have severe bleeding
disorders associated with clotting and
coagulation abnormalities caused by liver disease.
If the dog presents with a history of spontaneous nose bleeds of unknown origin, the veterinarian probably will also conduct a
coagulation profile, to see whether there are any identifiable primary
disorders in the dog's ability to form normal blood clots.