Not exact matches
A bleeding disorder known as von Willebrand disease — known as a
coagulopathy, this condition is associated with problems
in how the blood clots.
Background Acute traumatic
coagulopathy (ATC) is a common condition after traumatic injury and is known to be associated with an increase
in morbidity and mortality
in trauma patients.
Moreover, while still uncommonly used
in the clinic, researchers have successfully developed protein replacement therapy and gene therapy for a number of
coagulopathies.
Where a
coagulopathy e.g. DIC, or hypoproteinemia are present, or the patient with pancreatitis is deteriorating, fresh frozen plasma (10 - 20 ml / kg) may be benefi cial
in alleviating the
coagulopathy, hypoproteinemia and restoring a more normal protease - antiprotease balance.
Thrombocytopenia
in dogs with pancreatitis is often associated with DIC and additional tests of hemostasis (OSPT, APTT, FDP or D - dimer, fi brinogen, antithrombin III) are performed to determine if DIC or other
coagulopathies are present.
Is this a
coagulopathy that can be easily picked up on a PT and aPTT clotting test
in the veterinary emergency room?
In this VETgirl online veterinary continuing education blog, Dr. Garret Pachtinger reviews the rare but potentially deadly
coagulopathy, hemophilia.
Cases of vitamin K deficiency - responsive
coagulopathies have occasionally been documented
in dogs and cats with EPI and severe IBD.
Eventually, a cascade of systemic toxicosis (elevation of toxins
in the bloodstream), bleeding disorders (disseminated intravascular
coagulopathy), and organ failure may occur if the disease is not managed.
Indeed, very low concentrations of tocopherols and vitamin K
coagulopathies have been reported
in patients with EPI.
In dogs with
coagulopathies, low platelet count or on certain medications; the blood may not clot and may continue bleeding.
Later researchers discovered that the physiological mechanism responsible for this form of
coagulopathy — a dysfunction
in the blood's clotting...
Research Interests Critical care of polytrauma patients, troponin as a biomarker
in traumatic myocarditis, the application of Continuous Renal Replacement Therapy (dialysis) for companion animals with acute kidney failure, advanced therapeutic approaches to immune mediated hemolytic anemia, and novel laboratory assessment of
coagulopathies (including thromboelastography and platelet aggregometry).
At this time, there is insufficient evidence to recommend routine use of FFP
in pancreatitis cases unless there is a concurrent
coagulopathy.
* Sources: New Findings On The Effects Of Xylitol Ingestion
In Dogs from ASPCA - APCC 2006; Acute Hepatic Failure And Coagulopathy Associated With Xylitol Ingestion In Eight Dogs from ASPCA - APCC 2006, published in JAVMA (J Am Vet Med Assoc 2006; 229:1113 - 111
In Dogs from ASPCA - APCC 2006; Acute Hepatic Failure And
Coagulopathy Associated With Xylitol Ingestion
In Eight Dogs from ASPCA - APCC 2006, published in JAVMA (J Am Vet Med Assoc 2006; 229:1113 - 111
In Eight Dogs from ASPCA - APCC 2006, published
in JAVMA (J Am Vet Med Assoc 2006; 229:1113 - 111
in JAVMA (J Am Vet Med Assoc 2006; 229:1113 - 1117)