It means the
researchers coated protein - like molecules on solid surfaces in a highly ordered way to create materials similar to hard tissue surfaces, like bones or sea shells.
Image: Crystal structure of the complex between a domain repeat of
egg coat protein VERL (dark pink) and cognate sperm protein lysin (blue).
Protein trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus involves specific uptake into
coat protein complex II (COPII)-- coated vesicles of secretory and of vesicle targeting (v - SNARE) proteins.
But the sensor has a major shortcoming that prevents it from being used to detect biologically important peptides — such as neurotransmitters or fragments of
viral coat proteins — in biological samples: It doesn't work in water, the milieu of life.
The molecular details of how these viruses self - assemble protective protein containers around their cognate genomes in a specific and efficient manner have been revealed and illustrate multiple contacts
between coat proteins and dispersed packaging signals in the viral genome.
Fiers found it in the viral
coat protein M2, which creates a pore in the coat.
Nabel's team selected a bit of Ebola DNA that codes for one of the virus's
outer coat proteins, which allows the virus to wedge its way into host cells.
Wang homed in on a rhesus lymphocryptovirus (LCV), which had earlier been found to
express coat proteins similar to those of EBV.
Researchers at Karolinska Institutet in Sweden have obtained the first 3D snapshots of a sperm protein attached to a complementary egg
coat protein at the beginning of fertilisation.
The trial, to be funded by a grant of $ 20 million of public funds awarded by Congress, will study a genet - ically engineered form of HIV's
coat protein gp160.
The tight packing of the hydrogenases caused them to pair up into the catalytically active complex, and the closely
packed coat proteins prevented oxygen from diffusing in.
Two of the «first generation» vaccines, both based on genetically engineered forms of HIV's
coat protein gp120, have been tested for safety in Americans.
Again they sequenced the viruses they found in the various mosquito tissues, and they identified two new mutants, both with mutations in the same lock -
picking coat protein as the original Reunion mutant, results they published last year in Cell Host and Microbe.
The technique was dubbed TRICK (for Translating RNA Imaging
by Coat protein Knock - off).
By making transgenic, knock - in mice where the endogenous RNA is tagged with the stem loops of the MS2 phage, and bound to the
fluorescent coat protein, we can see all these events of mRNA from birth to death in living tissues.
Membrane trafficking within the Golgi complex is mediated by COPI (
coat protein complex I)- coated vesicles.
132 - character summary: PNNL - led
researchers coat protein - like molecules on solid surfaces in highly ordered manner, paving way for biomedical applications.
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Using X-ray crystallographic data collected at the European Synchrotron Radiation Facility (ESRF), Luca Jovine's research team at Karolinska Institutet first visualised the sperm - interacting regions of two
egg coat proteins, ZP2 in mammals (including humans) and VERL in the marine mollusc abalone (a classic model system of invertebrate fertilisation).
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This gene codes for
the coat protein of a bacteria - infecting virus, or bacteriophage.
The data suggest that transmembrane proteins can be taken up into COPII vesicles by direct interactions with
the coat proteins and may play a structural role in the assembly of the COPII coat complex.
The vaccine is a genetically engineered form of HIV's
coat protein, gp160, made by the US company MicroGeneSys.
Researchers at Protein Sciences Corporation, a small biotech in Meriden, Connecticut, genetically modified a virus that infects caterpillar cells to produces hemagglutinin,
a coat protein of the influenza virus that triggers antibodies.
Cytoplasmic domains of members of the p24 family of putative cargo receptors were shown to bind to coatomer,
the coat protein of COPI - coated transport vesicles.
The viruses also induce the bacteria to produce a second set of proteins that helps guide the assembly of P22 spheres, from
the coat proteins, on the outer surface of the cell membrane.
The glue's secret ingredients are tiny balls of sugar -
coated proteins.
The crucial insight is how
the coat protein assembles to form the virus» tight armor, says structural virologist Félix Rey of Centre National de la Research Scientique in Gif - Sur - Yvette, France.
Although some proteins use clathrin to traverse the endosome en route to the plasma membrane, others do not, and, until now, the general view has been that the direct path out of the trans - Golgi network (TGN) may involve tubular carriers formed without the intervention of
coat proteins.
The Amino Terminus of
the Coat Protein of Turnip crinkle virus Is the AVR Factor Recognized by Resistant Arabidopsis
We are taking a metabolic labeling - based approach to study H. pylori sugar -
coated proteins and to target H. pylori based on its unique sugars.
The high - resolution structure of a filamentous flexible plant virus shows that there is structural homology between
its coat protein and the nucleoproteins of an unrelated group of enveloped RNA animal viruses.