Sentences with phrase «cocaine abusers in»

According to a new imaging study, cocaine abusers in their 30s and 40s show brain changes more commonly seen in people over 60.

Not exact matches

Compared with drug - free people of the same age, the cocaine users also showed proportionally greater volume loss in prefrontal and temporal areas — the very areas that control the functions impaired in drug abusers.

Specifically, substance abusers (cocaine, methamphetamine, alcohol, heroin, and nicotine), but not marijuana abusers (14 ⇓ — 16), show reduced baseline availability of DA D2 receptors in striatum (reviewed ref.

Similarly, cocaine abusers (17, 18) and alcoholics (19, 20), but not marijuana abusers (16), show attenuated DA increases in striatum when challenged with a stimulant drug, although marijuana abusers with comorbid schizophrenia or risk for schizophrenia showed blunted DA increases to stimulants (21) and to stress (22).

Thus, our results showing no differences in D2 / D3 receptor availability (except for a trend in ventral striatum), using a larger sample (24 marijuana abusers) than that used for studies that identified reductions in striatal D2 / D3 receptors in alcoholics and cocaine abusers, indicate that marijuana abusers, different from other drug abusers, do not show significant striatal D2 / D3 receptor reductions.

Utility of crossover designs in clinical trials: Efficacy of desipramine vs. placebo in opioid - dependent cocaine abusers.