Sentences with phrase «cocaine in the brain slice»

It also proved possible to compare the potency of desoxypipradrol with the psychostimulant drug cocaine in the brain slice preparation.

Not exact matches

Indeed, by examining brain tissue and slices from the cocaine - addicted rats at various stages of withdrawal and craving, Wolf and her colleagues discovered that the incubation period and the subsequent spike in craving appeared to correlate with the appearance of atypical AMPA receptors on the surface of neurons in the NAc, which could help explain cocaine craving.

As shown previously in VTA - containing brain slices exposed to cocaine (Argilli et al., 2008), DA neurons showed significantly elevated potentiation of mEPSC amplitudes in PLE − / GFP + DA neurons in the presence of CM - MK801, which further demonstrates the lack of activity for CM - MK801 in PLE − neurons.

(D) For brain slices treated with CM - MK801, AMPAR - mediated mEPSC amplitude was increased in PLE − VTA DA neurons following cocaine treatment.