Sentences with word «cochlea»

«We saw impaired expression and splicing of genes with essential roles in cochlea development and auditory function,» Carstens said.

The number that developed varied, but in the base of cochlea, where the tissue received the most damage, hair cell numbers returned to about 40 % of the original.

A stem cell - derived neuron grafted onto a mouse cochlea in the inner ear that lacked neurons.

In fact, the brain's capacity for inventing new information - processing schemes is thought to explain the success of artificial cochleas, which have been implanted in the ears of approximately 100,000 hearing - impaired people around the world in the past few decades.

The membrane wiggles the three middle - ear bones, which transmit fluctuations to the fluid - filled, snail - shell - shaped cochlea of the inner ear.

The plate, in turn, creates ripples in a fluid - filled chamber akin to an unfurled human cochlea.

74 Cochlea's Spiral Plays Surprising Role in Hearing Deep inside your ear, the spiral - shaped cochlea helps translate reverberations into neurological signals...

The researchers chose NR because it is a precursor to the chemical compound nicotinamide adenine dinucleotide (NAD +), which had previously been shown by Dr. Brown and co-senior author Samie Jaffrey, MD, PhD, to protect cochlea nerve cells from injury.

These findings helped lead to the development of prototypes of the electronic cochlea implants now available today.

The ear bones will package the sound to the ear cochlea (fluid) in the form of a special vibration where it is converted into electric pulses for the brain to interpret.

A trio of small bones linked to the eardrum picks up the vibrations and sends them to the inner ear's fluid - filled cochlea.

Recently Sarpeshkar adapted one of his audio chips into a biologically inspired radio frequency cochlea chip, which enables applications for cognitive and ultrahigh - band radios in the future.

While you were under they implanted my microdot into your right cochlea and wired it into your auditory cortex.

Using this method, these authors were able to reconstruct a cleared guinea pig cochlea in 3D.

Removal of an unbroken cochlea indicated the initial success of the surgery, which was later confirmed by song analysis (see below).

Researchers in Japan who evaluated the risks and efficacy of transplanting two varieties of stem cells into mouse cochlea have...

The film is also aurally ravishing; in his fourth project with the director, Radiohead guitarist Jonny Greenwood composes a score that encompasses everything from an opening blast of cochlea - rattling drone to silkiest jazz piano.

Nevertheless, the surprising effectiveness of artificial cochleas — together with other evidence of the brain's adaptability and opportunism — has fueled optimism about the prospects for brain /?

The statocysts contains a tiny grain of calcium nested in a fluid - filled sac lined by hairs — not dissimilar to a human cochlea.

Deep inside your ear, the pea - size, spiral - shaped cochlea helps translate reverberations from the outside world into neurological signals that we perceive as sound.

San Diego — based Otonomy, which raised $ 115 million in a 2014 initial public offering, is in clinical trials for a drug that could quiet the overexcitement of the signaling between nerve cells in the cochlea that is linked to tinnitus.

Instead of transmitting sound in waves that float through the air and into your ears, bone conduction gets noise to your cochlea — that's the auditory part of the inner ear — just by vibrating the bones in your skull.

Your baby's hearing system (cochlea and peripheral sensory end organs), which began fine development during week eighteen, is now completely formed, and over the next few weeks, she'll become increasingly sensitive to sound.

He recovered, but the treatment destroyed the hair cells in his cochlea, where sound vibrations are translated into neural impulses.

As the cochlea's fluid moves, about 15,000 hair cells sitting in it, each tuned to a particular frequency, pick up the motions; the cochlear nerve translates the movements into auditory messages that are sent to the brain.

The inner ear comprises the hearing organ or cochlea, together with the five balance organs (the saccule, utricle and three semicircular canals), which contain the sensory cells, or hair cells, that detect mechanical vibrations and convert them into electrical signals.

During this prehearing period, the scientists discovered, the rodents have bursts of activity in certain cells — called support cells — in their cochleas.

It's hard to create cochlear implants with more frequencies, known as channels, because each extra one needs to stimulate auditory nerves at a different point along the cochlea.

In patients with middle - ear implants, the cochlea is functional, but one of the ossicles — the stapes — doesn't vibrate with enough force to stimulate the auditory nerve.

Standard cochlear implants function by stimulating nerves using an electrode placed inside the cochlea, a tiny spiral cavity inside the ear.

The new device would use the same type of sensor, but the signal it generates would travel to a microchip implanted in the ear, which would convert it to an electrical signal and pass it on to an electrode in the cochlea.

The gene makes prestin, a protein in hair cells of the cochlea, which is the organ in the inner ear where sonar signals are accepted and amplified.

Delicate bones in the middle ear, known as ossicles, convey the vibrations of the eardrum to the cochlea, the small, spiral chamber in the inner ear that converts acoustic signals to electrical.

Specifically, it targets the cochlea, a snail - like structure in the inner ear where sensitive cells convey sound to the brain.

While previous vectors have only been able to penetrate the cochlea's inner hair cells, the first Nature Biotechnology study showed that a new synthetic vector, Anc80, safely transferred genes to the hard - to - reach outer hair cells when introduced into the cochlea (see images).

When a corrected Ush1c gene was introduced into the inner ears of the mice, the inner and outer hair cells in the cochlea began to produce normal full - length harmonin.

And then in the opposite ear, I developed Meniere's disease, which is a problem with controlling fluid inside the cochlea, progressively damaging the hair cells there.

Existing implants can't be worn all the time because only a small part of the device is actually inside the cochlea.

Instead, they translate sound into electrical signals that are used to electrically stimulate the cochlea — a spiral - shaped part of the inner ear attached to the auditory nerve.

One clinical trial involves the drug CGF166, a one - time gene therapy, which, if proven successful in humans, could regenerate new hair cells within the cochlea that can signal the part of the brain that processes sound.

Another important difference between bird and human hearing occurs in the inner ear, and especially in the cochlea — the structure containing the vibration - sensitive «hearing» hairs.

«Boubaness» or «kikiness» arises between two stimuli that are otherwise utterly dissimilar: an image formed on the retina versus a sound activated in the cochlea of the ear.

Normally, cochlear implants receive their signal and power through an induction loop linking the implant in the cochlea to an external unit containing the microphone and battery.

While surgery carries a risk of infection and nerve damage to the cochlea, experience has shown that these risks are very low, says Janssen.

Compared with a normal mouse cochlea (top), cisplatin exposure reduces the number of outer hair cells (middle).

Sensory hair cells in the cochlea of a Beethoven mouse treated with TMC2 gene therapy.

The therapy promotes the regrowth of crucial hair cells in the cochlea, the part of the inner ear which registers sound.

The viruses had been engineered to be harmless while also smuggling a gene called Atoh1 into cells lining the scala media — the key chamber of the cochlea, containing the hair cells.