Dr. Ray undertook this study because of the large number of immigrants in Ontario from East Africa, particularly Ethiopia and Eritrea, who are known to metabolize
codeine into morphine faster than people from some other parts of the world.
Typically, the body makes an enzyme that breaks down
codeine into morphine, which muzzles pain.
Not exact matches
While
codeine has traditionally been considered safe for breastfeeding mothers, it is known that the drug is converted
into morphine, which is transmitted through the breastmilk to the baby, and this can lead to depression of the central nervous system and apnea, which can, in rare cases, be fatal.
Other opiates used as medicines — morphine, meperidine and
codeine — are excreted
into the milk in minimal amounts and are compatible with breastfeeding, as are benzodiazepines, as long as they are taken in controlled doses..
Senate Wednesday raised the alarm that the recently banned
codeine syrups and other related drugs have now found their ways
into the Sambisa forest inhabited by...
For them, almost no
codeine is converted
into morphine, and there's no pain relief.
Other groups had already supplied yeast with genes for the second half of the pathway, which converts a similar intermediate called R - reticuline
into codeine, morphine, and the like.
The last piece of the poppy puzzle is now in hand: Plant geneticists have isolated the gene in the plant that carries out the last unknown step in converting glucose and other simple compounds
into codeine, morphine, and a wide variety of other medicines.
Weiner mixes a solution of a respective drug
into a pan of water, using substances such as Aspirin,
Codeine, Molly, Marijuana, 5 - hour Energy and Vodka.