Sentences with phrase «coding nucleotide sequences»

Notophthalmus viridescens, an urodelian amphibian, represents an excellent model organism to study regenerative processes, but mechanistic insights into molecular processes driving regeneration have been hindered by a paucity and poor annotation of coding nucleotide sequences.

Not exact matches

DNA, made up of four nucleotide molecules in a sequence, is a code that can be edited and written — not unlike software.

The Genographic Project: Testing My Maternal Ancestry Commercial testing companies do not need to test my whole genetic sequence — all 3 billion nucleotides, the «letters» of the genetic code — to tap into my past.

That sort of resolution should be good enough to determine the sequence of all the nucleotide bases in the human genetic code.

It starts with a long DNA strand — called a scaffold — that has a precise sequence of the four molecular units, or nucleotides, dubbed A, C, G, and T, with which DNA spells out its genetic code.

The blade, he found, is an enzyme that always cuts the viral DNA code where it finds a particular short sequence of nucleotides.

This mutation probably happened because the sequence of three nucleotides was repeated, and this repeat just happened to be in the right place in waterhemp's genetic code.

Extensive research has already examined the function of microRNAs, a category of small evolutionarily conserved noncoding RNAs about 22 to 24 nucleotides in length that target protein - coding genes in a sequence - specific manner.

First the two researchers narrowed the possible location of the lin - 4 gene to a sequence of DNA 700 nucleotides long, about one - third the size of a typical protein - coding gene.

The third is a method implemented by Reich for reading the genetic codes of 1.2 million carefully chosen variable parts of DNA (known as single nucleotide polymorphisms) rather than having to sequence entire genomes.

The human genome contains about 3 billion base pairs, but only about 2 percent of these base pairs represent protein - coding genes, meaning that whole - exome sequencing measures the genetic alterations focused on a small but very important fraction of the genome (as opposed to techniques of whole genome sequencing, which measures every nucleotide across the entire genome, regardless of whether these genes are expressed or silent).

Synonymous single - nucleotide polymorphisms (SNPs) do not produce altered coding sequences, and therefore they are not expected to change the function of the protein in which they occur.

Silent mutations occur when the change of a single DNA nucleotide within a protein - coding portion of a gene does not affect the sequence of amino acids that make up the gene's protein.

While the two actin isoforms differ by only four amino acids, their mRNA coding sequences differ by almost 13 percent because of «silent» nucleotide differences that nevertheless encode the same amino acids.

Delbrück's summer course on bacteriophages in 1945 at Cold Spring Harbor in New York set in motion the chain of events that led to understanding the genetic code by which the sequence of the nucleotides in DNA is translated into the sequence of amino acids in a protein.

To reveal the structural genetic code, researchers examine chromatin from its sequence of nucleotides to the organisation of an entire genome.

The researchers analyzed hundreds of human transcription factors, which are proteins that read the genetic information coded in DNA's sequence of four nucleotide bases — adenine (A), cytosine (C), guanine (G) and thymine (T)-- and pass that on to RNA molecules.

Genomic sequencing of the isolated virus revealed that it is closely related to Tembusu virus (a mosquito - borne Ntaya group flavivirus), with 87 — 91 % nucleotide identity of the partial E (envelope) proteins to that of Tembusu virus and 72 % of the entire genome coding sequence with Bagaza virus, the most closely related flavivirus with an entirely sequenced genome.

Sequencing and BLAST analysis recealed a 87 — 91 % / 87 % nucleotide identity with a partial coding sequence from the Tembusu / Sitiawan virus E gene (encoding the envelope protein)(Fig. 7A).

Nucleotide sequence comparisons of the E protein (A), NS5 protein (B) and the genome coding polyprotein (C).

Molecular evolutionary analysis of the entire coding sequence in the eight representative mammalian species: Monotremes (platypus), Marsupials (opossum) and Eutherians (mouse, rat, dog, rhesus monkey, chimpanzee and human), revealed no excessive non-synonymous nucleotide changes in comparison with synonymous changes.

Kazuko Nishikura, Ph.D., discovered a mechanism of RNA regulation through which cells can make discrete changes in the sequence of nucleotides — the «letters» in the RNA code, ultimately affecting the protein product.