An out - of - frame overlapping reading frame in the ataxin - 1
coding sequence encodes a novel ataxin - 1 interacting protein.
Not exact matches
The major function of DNA is to
encode the
sequence of amino acid residues in proteins, using the genetic
code.
The genetic
code is the set of rules by which information
encoded in genetic material (DNA or RNA
sequences) is translated into proteins (amino acid
sequences) by living cells.
In mammalian mitochondria there are two
codes for methionine, rather than one, and one of the stop codons, which usually terminates a protein
sequence,
encodes tryptophan instead.
While the two actin isoforms differ by only four amino acids, their mRNA
coding sequences differ by almost 13 percent because of «silent» nucleotide differences that nevertheless
encode the same amino acids.
The researchers performed the same experiment, editing the γ - actin gene to
encode the β - actin protein but were only able to change the
coding sequence for three of the four amino acides.
You may also have learned about the genetic
code, by which the
sequences of DNA
encode amino acids (worked out by Nirenberg, Khorana and colleagues by 1961).
Only 62 % of the genome is predicted to be
coding sequence,
encoding 888 proteins and 41 stable RNA species.
The
coding portion of the first CCHa2 - R
coding exon was replaced with
sequence encoding the strong GAL4:: p65 transcriptional activator (Fig 2E; CCHa2 - R - GAL4:: p65).
An adult C. elegans with GFP
coding sequence inserted into a histone -
encoding gene.
In other cases alternative transcripts have introns interrupting the
coding sequence, resulting in a truncated ORF that is likely to
encode a non-functional receptor.
Sequencing and BLAST analysis recealed a 87 — 91 % / 87 % nucleotide identity with a partial
coding sequence from the Tembusu / Sitiawan virus E gene (
encoding the envelope protein)(Fig. 7A).
Two adenovirus mRNAs have a common 5 ′ terminal leader
sequence encoded at least 10 kb upstream from their main
coding regions
In each of the BAC transgenic vectors, endogenous protein
coding sequences have been replaced by
sequences encoding the EGFP reporter gene.