On average, changing a single
codon reduced the fitness of the bacteria, by 0.01 procent per generation.
Brandis and Hughes changed many different codons and showed that changing even a single codon in the gene for this protein into any one of the alternative «synonymous»
codons reduced the «fitness» of Salmonella.
Not exact matches
Reducing this variation by RY recoding of purines (R) and pyrimidines (Y) on the third
codon position (SM4) made the c123 tree topology more similar to the c12 topology (Fig. 2 and fig.