Sentences with phrase «codon usage»
Codon usage refers to how often certain combinations of genetic code units, called codons, are used to build proteins in an organism. Different organisms have unique preferences for which codons they use more frequently, even when coding for the same protein. This can affect how efficiently proteins are produced, as certain codons may be read more quickly or accurately by the cellular machinery. Studying codon usage can give insights into the genetic makeup and characteristics of an organism. Full definition
Maximum likelihood estimation of ancestral codon usage bias parameters in Drosophila Nielsen, R., V. L. B. DuMont, M. J. Hubisz, and C. F. Aquadro.
nielsenlab.org
Maximum likelihood estimation of ancestral codon usage bias parameters in Drosophila.
Mutation - selection models of codon substitution and their use to estimate selective strengths on codon usage Yang, Z. and R. Nielsen.
Mutation - selection models of codon substitution and their use to estimate selective strengths on codon usage.
This tiny change in fitness is big enough for evolution to select the «fittest» DNA sequence and causes what is called «codon usage bias» — the widespread use of particular codons to make highly expressed proteins.
All living things use the same language, but codon usage and tRNA availability varies among different organisms and different tissues — just as the spelling «colour» predominates among the British, while «color» is more common among Americans.