Sentences with phrase «codons instead»

In ciliated protozoans, two of the standard stop codons instead encode glutamine.

Not exact matches

In mammalian mitochondria there are two codes for methionine, rather than one, and one of the stop codons, which usually terminates a protein sequence, encodes tryptophan instead.

Jason Chin at the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK, and colleagues previously showed that it was possible to reassign one of these stop codons to incorporate an «unnatural» amino acid instead, and last year they engineered nematode worms to manufacture such proteins.

Theoretically, once a particular codon — say, TAG — has been removed from a genome, the cell's protein - making machinery could be reprogrammed to assign TAG to an amino acid, instead of being a stop signal.

The researchers found that the codon, which should have signaled a halt to protein production, instead acted as the blueprint for a previously unknown amino acid, pyrrolysine.