Sentences with phrase «cofactor of»

Copper is an essential cofactor of a key oxidative enzyme called superoxide dismutase.

Vitamin B - 12, a water - soluble B vitamin and essential cofactor of methionine synthase in 1 - carbon metabolism, has been known to affect genomic DNA methylation

Not only does selenium play a critical role in cancer prevention as a cofactor of glutathione peroxidase, selenium also works with vitamin E in numerous other vital antioxidant systems throughout the body.

AIMS / HYPOTHESIS: A natural cofactor of mitochondrial dehydrogenase complexes and a potent antioxidant, alpha - lipoic acid improves glucose metabolism in people with Type II (non-insulin-dependent) diabetes mellitus and in animal models of diabetes.

Indeed, vitamin C may be a critical cofactor of dopamine beta - hydroxylase and also may protect membrane phospholipids acting as a scavenger of ROS.

Manganese is an antioxidant and cofactor of enzymes that produce collagen.

Reference: Immunity, «The PIAS - like coactivator Zmiz1 is a direct and selective cofactor of Nortch1 in T - cell development and leukemia,» published online Oct. 27

As a cofactor of certain proteins, it plays an essential role in oxygen transport and metabolism.

A cofactor of glutathione peroxidase (one of the body's most important internally produced antioxidant enzymes), selenium also works with vitamin E in a number of vital antioxidant systems.

Almonds are a very good source of manganese and copper, two trace minerals that are essential cofactors of a key oxidative enzyme called superoxide dismutase.

«The study was incredibly challenging because, to study bacterial cofactors of HIV risk, the team needed to identify samples collected just prior to HIV acquisition,» she said.

Navy beans are a very good source of manganese and a good source of copper, trace minerals that are essential cofactors of a key oxidative enzyme called superoxide dismutase.

Almonds are a very good source of manganese and copper, two trace minerals that are essential cofactors of a key oxidative enzyme called superoxide dismutase.

Not exact matches

In addition, brown rice is high in selenium, which is a trace element nutrient that functions as cofactor for reduction of antioxidant enzymes.

Retinoic acid receptors are one of these cofactors, recruiting additional proteins to open DNA.

The current paper shows that treating with retinoids simultaneously with anti-estrogen therapies may pull cofactors for progesterone receptors away from their posts, disallowing their ability to open DNA at the point of CK5 and keeping the growth of dangerous CK5 + cells in check.

This is how progesterone boosts CK5 + cells — like tiny gatekeepers, progesterone receptors and their cofactors sit in front of the gene CK5, opening the doors of DNA to be read at this point.

The resulting poisoned cofactor does not function properly and derails the ability of Enterobacteriaceae to generate energy in the inflamed gut.

The catalytic center of vanadium nitrogenase: an iron - vanadium cofactor with an unusual carbonate ligand.

What initially appears to be a slight difference has far - reaching effects on the geometric and electronic structure of the cofactor.

HIV - 1 Entry Cofactor: Functional cDNA Cloning of a Seven - Transmembrane, G Protein - Coupled Receptor

A cofactor for HIV - 1 (human immunodeficiency virus - type 1) fusion and entry was identified with the use of a novel functional complementary DNA (cDNA) cloning strategy.

The researchers were able to inhibit the activity of the enzyme using the toxic gas carbon monoxide (CO) to show how the inhibitor binds to the iron molybdenum cofactor (FeMoco).

Einsle is studying the microstructure of the heart of the enzyme: a large metal core called the iron molybdenum cofactor (FeMoco).

First author Vignesh Kasinath said, «It took three years of work to obtain this high - resolution structure of all the parts, or subunits, that make up a functional PRC2, as well as visualize how additional protein subunits, called cofactors, may help regulate its activity.

You have to get yourself into that peculiar state of mind where you can go to an issue of Nature and read a paper entitled «Glucose is an essential cofactor for function of the glucose porter in vitro» from top to bottom and think «Wow» and then aim for similar lofty heights.

Previous studies have shown that flavonoids have the capacity of chelating the active site as well as acting as cofactor or substrate of tyrosinase, thus inhibiting its effect.

Hegeman, C. E., Hayes, M. L., and Hanson, M. R. (2005) Substrate and cofactor requirements for RNA editing of chloroplast transcripts in Arabidopsis in vitro.

Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion - related acute lung injury.

Mammal sirtuins are NAD + - dependent deacetylases that use NAD + as cofactor for catalyzed reactions to cleave acetyl groups from acetylated lysine residues of target proteins, generating nicotinamide (NAM) and 2 ′ - O - acetyl - ADP - ribose.

Some of the most fascinating catalysts in nature display complex inorganic cofactors and perform chemical transformations (water reduction and oxidation, carbon dioxide reduction, dinitrogen reduction, dioxygen reduction) that are arguably prerequisites for the advance of society in the current context of limiting energy resources and environmental concerns.

So, the present results attributed the increment of the immunohistochemical parameters incidence may be related to the environmental cofactors due to changes in reproductive factors and lifestyle in our country.

This laboratory studies aspects of one - carbon metabolism, namely the micronutrients folate and vitamin B12, which serve as substrate and cofactor, respectively, in the methionine cycle and homocysteine, which is a branch - point metabolite in the methionine cycle and an independent risk factor for cardiovascular disease (coronary artery, cerebrovascular and peripheral vascular disease), cognitive impairment (Alzheimer's disease) and complications of pregnancy (neural tube defects).

What's next: Studies revealing that the cofactor binding sites of Paps are functional and that they are able to transfer cofactors — non-protein compounds required by enzymes to function — could provide insight into how they are assembled into the complex.

The KININ meeting occurs every three years, assembling scientists and clinicians involved in the field of bradykinin (kinins) and its related proteins (enzymes, cofactors, substrates, receptors, proteolytic systems, disease states, and developing therapies) for presentation of the latest ideas, research, drug development and therapeutics in these biologic systems.

There are 2 types of hydrogens in the catalytic cofactor (called FeMo - co): one located in a bridging position where it binds to two iron atoms (a bridging hydride), and one on a nearby sulfur atom ligands (basically a protonated sulfur atom: S - H).

Homeotic function of Drosophila Bithorax - Complex miRNAs mediates fertility by restricting multiple Hox genes and TALE cofactors in the central nervous system.

These modifications of p53 are believed to fine tune p53 - dependent gene regulation and cell fate decisions by affecting p53 protein stability, DNA binding affinity and interactions between p53 and other transcription cofactors.

Human oligodendroglial cells express low levels of C1 inhibitor and membrane cofactor protein mRNAs.

Nitric oxide (NO) is endogenously synthesized by nitric oxide synthases (NOSs) which convert L - arginine to L - citrulline and NO in the presence of oxygen and several cofactors.

LPL is a pivotal player in TG metabolism, as mutations in LPL or in its cofactors (ApoC - II, glycosylphosphatidylinositol - anchored high - density lipoprotein — binding protein 1, lipase maturation factor 1) account for the majority of monogenic hypertriglyceridemia cases (25).

Functional analysis of substrate and cofactor complex structures of a thymidylate synthase - complementing protein.

Crystal structure of an alanine - glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor.

In 2014, in partnership with San Diego Zoo Global's (SDZG) Frozen Zoo and Cofactor Genomics, Revive & Restore sequenced the genomes of four, carefully selected Black - footed Ferret samples to assess some preliminary questions about the species» history and its conservation:

(b) A series of heme cofactors in the protein MtrF illustrating the multi-cytochrome nature of the transport and the molecular structures involved (image is adapted from Breuer, M. et al.).

Many of the nutrients within almonds (like magnesium and vitamin E) are actually cofactors to glutathione.

Recipes like my almond and rice snack bars and riced broccoli salad are great examples of foods that incorporate those glutathione building blocks and cofactors like almonds.

Magnesium is an important cofactor in the synthesis of neurotransmitters like serotonin and dopamine.

A clear, direct, one - to - one relationship between pesticides and polio over a period of 30 years, with pesticides preceding polio incidence in the context of the CNS - related physiology just described, leaves little room for complicated virus arguments, even as a cofactor, unless there exists a rigorous proof for virus causation.

Replete with a plethora of high - caliber performance ingredients and essential cofactor vitamins, the Extend powder from Scivation can provide athletes a critically important augmentation tool that could prove to transform their gains and growth in sustainable ways.