Not exact matches
Post-partum depression poses substantial adverse consequences for mothers and their infants via multiple direct biological (i.e., medication exposure, maternal genetic
factors) and environmental (i.e., life with a depressed mother) mechanisms.8, 9 From the earliest newborn period, infants are very sensitive to the emotional states of their mothers and other caregivers.10, 11 Maternal mood and behaviour appear to compromise infant social, emotional and
cognitive functioning.11 - 15 As children grow, the impact of maternal mental illness appears as
cognitive compromise, insecure attachment and behavioural difficulties
during the preschool and school periods.6,16 - 19
In a large population - based study of randomly selected participants in Germany, researchers found that mild
cognitive impairment (MCI) occurred significantly more often in individuals diagnosed with a lower ankle brachial index (ABI), which is a marker of generalized atherosclerosis and thus cumulative exposure to cardiovascular risk
factors during lifetime.
Biological
factors such as maternal nutritional status
during pregnancy, low infant birth weight, premature birth, poor infant physical growth and nutritional status at follow - up were not as strongly linked to
cognitive ability as the socio - environmental
factors assessed
during the study: home environment, maternal depression, parental education and socio - economic status.
In the Lu laboratory, we aim to elucidate the signaling cascades that establish neural circuit connections
during brain development, to understand how sensory experiences and environmental
factors affect neural circuit wiring and
cognitive behaviors, and to identify novel
factors required to maintain the health of neural circuits
during aging.
The most recent follow - up study reported associations between duration of breastfeeding and childhood
cognitive ability and academic achievement extending from 8 to 18 years in a New Zealand cohort of 1000 children.19 This study found that these effects were significant after controlling for measures of social and family history, including maternal age, education, SES, marital status, smoking
during pregnancy, family living conditions, and family income, and measures of perinatal
factors, including gender, birth weight, child's estimated gestational age, and birth order in the family.
Factors which were found to be significantly related to lower cognitive scores included maternal characteristics (low maternal educational attainment and younger age) and socio - economic factors (living in an area of deprivation, an urban area of residence, larger family size and living in persistent poverty during the early
Factors which were found to be significantly related to lower
cognitive scores included maternal characteristics (low maternal educational attainment and younger age) and socio - economic
factors (living in an area of deprivation, an urban area of residence, larger family size and living in persistent poverty during the early
factors (living in an area of deprivation, an urban area of residence, larger family size and living in persistent poverty
during the early years).
During an initial assessment, children completed self - report measures assessing
cognitive and interpersonal vulnerability
factors to depression.
Maternal smoking
during pregnancy and children's
cognitive and physical development: a causal risk
factor?