"Cognitive fatigue" is a term that refers to feeling tired or worn out mentally. It happens when our brain gets exhausted from thinking, concentrating, or processing information for a long time.
Full definition
Researchers are studying the mechanisms
of cognitive fatigue, toward the goal of developing effective interventions.
«This suggests that older adults should adopt adequate drinking behaviors to
reduce cognitive fatigue and potentially enhance the cognitive benefits of regular exercise participation,» the researchers wrote.
Individuals with neurological damage often report difficulties
with cognitive fatigue, a subjective lack of mental energy that is perceived to interfere with daily activities.
«These methods will greatly contribute to the advancement of our knowledge of the mechanisms of
cognitive fatigue in MS,» he noted, «and will have the potential to advance the study of other neurological conditions.»
Kessler Foundation researchers have authored a new article that further elucidates the mechanisms
for cognitive fatigue, a disabling symptom that affects many individuals after traumatic brain injury (TBI).
Bing Yao, PhD, has been awarded a $ 560,000 grant from the National Multiple Sclerosis Society to study the association
between cognitive fatigue and brain iron concentration, as estimated by MRI susceptibility contrast imaging.
East Hanover, NJ — January 18, 2018 — Ekaterina Dobryakova, PhD, research scientist in Traumatic Brain Injury Research at Kessler Foundation, received an award from the New Jersey Health Foundation to study how performance feedback
influences cognitive fatigue levels in individuals with TBI.
Novel study demonstrates potential for nonpharmacologic intervention for
treating cognitive fatigue in individuals with multiple sclerosis
New Jersey Health Foundation funds study of the effects of feedback on
cognitive fatigue levels in traumatic brain injury
But maintaining the behaviors that send those signals, such as answering questions without hesitation, gets increasingly hard
as cognitive fatigue creeps in over the course of a shift; to excel, workers need something stronger than a cup of coffee.
Neuroimaging findings show overlap in activity in the anterior cingulate cortex, suggesting a pattern of self - regulation in the brain triggered by cognitive fatigue
, research scientist at Kessler Foundation, received a grant for $ 408,000 from the National Multiple Sclerosis Society to study factors influencing
disabling cognitive fatigue in the MS population, toward the goal of developing novel endogenous treatments.
«We looked specifically at the relationship between individuals «self - reported fatigue and objective measures of
cognitive fatigue using state - of - the - art neuroimaging,» explained Helen M. Genova, Ph.D., research scientist in Neuropsychology & Neuroscience Research at Kessler Foundation.
A new study by Kessler Foundation scientists sheds light on the mechanisms
underlying cognitive fatigue in individuals with multiple sclerosis.
hat cognitive fatigue may be the brain's way of signalling to itself that the effort required for the task no longer merits the rewards received.»
Kessler Foundation researchers have authored a new article that has implications for our understanding of the relationship
between cognitive fatigue and effort and reward.
The study investigated the neural correlates
of cognitive fatigue in MS utilizing three neuroimaging approaches: functional magnetic resonance imaging (fMRI), which allows researchers to look at where in the brain activation is associated with a task or an experience; diffusion tensor imaging (DTI), which allows researchers to look at the health of the brain's white matter; and voxel - based morphometry (VBM), which allows researchers to investigate structural changes in the brain.
A recent article by MS researchers describes a new nonpharmacological approach to
reduce cognitive fatigue, a disabling symptom reported by as many as 90 % of individuals with multiple sclerosis (MS).
The study, which was conducted in healthy participants, broadens our understanding of disease entities that are associated with a lower threshold
for cognitive fatigue, such as multiple sclerosis, brain injury, stroke and Parkinson disease.
This research - dedicated Center is increasing our fundamental knowledge of factors that contribute to disability, such
as cognitive fatigue, spatial neglect, and disorders of emotional processing, executive function and processing speed.
Ekaterina Dobryakova, PhD, research scientist at Kessler Foundation, received a grant for $ 408,000 from the National Multiple Sclerosis Society to study factors influencing
disabling cognitive fatigue in the MS population, toward the goal of developing novel endogenous treatments.
Ekaterina Dobryakova, Ph D., a postdoctoral fellow in Kessler Foundation Neuropsychology and Neuroscience Research received a competitive research award from the New Jersey Neuropsychological Society to study whether motivation
influences cognitive fatigue and the brain regions associated with it in patients with multiple sclerosis (MS).
Injury and disease of the brain increase the likelihood of
cognitive fatigue, which can be disabling.
Genova H et al: Examination of
cognitive fatigue in multiple sclerosis using functional magnetic resonance imaging and diffusion tensor imaging» was published on Nov. 1 in PLoS One.
Cognitive fatigue is fatigue resulting from mental work rather than from physical labor.
«Identifying a network of fatigue - related brain regions could reframe the current construct of
cognitive fatigue and help define the pathophysiology of this multifaceted yet elusive symptom of MS,» said John DeLuca, Ph.D., VP of Research & Training at Kessler Foundation.
This is the first study to use neuroimaging to investigate aspects of
cognitive fatigue.
The article, «The relationship between outcome prediction and
cognitive fatigue: a convergence of paradigms,» was epublished ahead of print on May 25, 2017, in Cognitive, Affective, & Behavioral Neuroscience.
«Link found between
cognitive fatigue and effort and reward: Neuroimaging findings show overlap in activity in the anterior cingulate cortex, suggesting a pattern of self - regulation in the brain triggered by cognitive fatigue.»
They were, suggesting that
cognitive fatigue may be the brain's way of signalling to itself that the effort required for the task no longer merits the rewards received.»
Because of poor correlation between self - reports of
cognitive fatigue and tests of cognitive performance, scientists are looking at more objective measures, such as correlations with neuroimaging findings.
The article, «
Cognitive fatigue in individuals with traumatic brain injury is associated with caudate activation,» was published online on August 21, 2017, in Scientific Reports.
«
Cognitive fatigue after TBI linked with activation of caudate: Findings underscore the role of the caudate nucleus in the mechanism of cognitive fatigue in traumatic brain injury.»
«These results are consistent with findings in our related research in the multiple sclerosis (MS) population,» said Dr. Wylie, the lead author, «which suggests that the TBI and MS populations share a mechanism for
cognitive fatigue.»
Under the leadership of John DeLuca, PhD, senior VP for Research & Training, and Nancy Chiaravalloti, PhD, director of Neuropsychology & Neuroscience Research, scientists have made important contributions to the knowledge of cognitive decline in MS. Clinical studies span new learning, memory, executive function, attention and processing speed, emotional processing, employment and
cognitive fatigue.
The goal is to see whether a behavioral intervention that is based on providing performance feedback can effectively reduce levels of
cognitive fatigue, a finding that would have implications for individuals with other types of neurological conditions who are affected by disabling fatigue.
«Specifically, the results will provide missing evidence on the brain areas involved in
cognitive fatigue,» she noted, «as well as how their functioning is related to cognitive fatigue during task performance.
Ph.D., and Nancy Chiaravalloti, Ph.D., director of Neuropsychology & Neuroscience Research, scientists have made important contributions to the knowledge of cognitive decline in MS. Clinical studies span new learning, memory, executive function, attention and processing speed, emotional processing and
cognitive fatigue.
Cognitive symptoms, including
cognitive fatigue, are a common but under recognized complication of MS. Individuals with MS often report experiencing cognitive fatigue, (fatigue resulting from mental work rather than from physical labor) as one of their most debilitating symptoms.
«This study aims to determine whether motivation results in activation of the network of regions in the brain thought to be impaired in
cognitive fatigue,» said Dr. Chiaravalloti, director of Neuropsychology & Neuroscience Research.
Under the leadership of John DeLuca, PhD, senior VP of Research & Training, and Nancy Chiaravalloti, PhD, director of Neuropsychology & Neuroscience and TBI Research, scientists have made important contributions to the knowledge of cognitive decline in MS. Clinical studies span new learning, memory, executive function, attention and processing speed, emotional processing and
cognitive fatigue.
Healthy participants, as well as individuals with MS who report
cognitive fatigue on a daily basis, will undergo functional MRI of the brain.