Lack of access to early trauma and family dysfunction variables as well as measures of general
cognitive impairment at baseline.
The goal was to investigate the ability of J147 to rescue
cognitive impairment at a late stage in the disease as an indicator of its potential to rescue cognitive impairment in humans with AD.
Compared with men with sodium levels of 141 - 142 mmol / L, men with levels of 126 - 140 mmol / L were 30 % more likely to have
cognitive impairment at baseline and 37 % more likely to experience cognitive decline over time.
Not exact matches
Regardless of the specific mechanism
at play in our bodies, the most recent recommendations suggest that working out twice a week may be beneficial in curbing some symptoms of mild
cognitive impairment (MCI), a stage that precedes the development of Alzheimer's in some older people.
The «Elder Investment Fraud and Financial Exploitation Prevention Program» (EIFFE Prevention Program) educates healthcare and legal professionals to recognize when their older patients and clients may be vulnerable to or victims of financial abuse, particularly those patients with mild
cognitive impairment, and then to refer these
at - risk patients to State Securities Regulators, local adult protective services professionals or for further screening and assistance as needed.
An August 2015 editiorial in the British Journal of Sports Medicine, [41] said that autopsy studies - many conducted in Boston
at the Center for the Study of Chronic Traumatic Encephalopathy - and a study reporting that retired NFL players who began playing football before age 12 demonstrated greater levels of
cognitive impairment in their 40s - 60s than those who started later, [40] «raises concern that an accumulation of undiagnosed subconcussive head trauma may lead to (or be a leading factor) for CTE.»
I know the point
at which insufficient O2 saturation becomes a concern for permanent
cognitive impairment.
Speech Language Pathologists
at CVMC can help chemotherapy patients experiencing
cognitive impairment learn coping strategies and improve
cognitive skills.
But a new study shows that, in mice
at least, cosmic radiation likely causes
cognitive impairment.
«
Cognitive aging is not a disease or a level of
impairment — it is a lifelong process that affects everyone,» explains lead author Dr. Sharon K. Inouye, Director of the Aging Brain Center
at the Institute for Aging Research, Hebrew SeniorLife in Boston, Massachusetts and Professor of Medicine, Harvard Medical School.
The medications excel
at quelling hallucinations and delusions, yet largely fail to address schizophrenia's debilitating
cognitive and social
impairments, while increasing risk for movement disorders, weight gain, and other metabolic and cardiovascular side effects.
Ongoing studies
at Uppsala University in Sweden have shown that the chemical agent dubbed Pittsburgh Compound - B, or PIB, is a highly accurate marker of plaque buildup and that its abundance in the brain can predict whether patients with mild
cognitive impairment will develop Alzheimer's — and when that decline will likely start.
In total, the analysis looked
at 26 types of side effects including erectile dysfunction, sleep disturbance and
cognitive impairment.
Researchers used accelerometers to measure the daily physical activity of participants, all of whom are in late middle - age and
at high genetic risk for Alzheimer's disease, but presently show no
cognitive impairment.
Researchers
at Karolinska Institutet, and the Sahlgrenska Academy
at Gothenburg University in Sweden have identified a gene variant linked to psychotic symptoms and
cognitive impairment in people with bipolar disorder.
People with mild
cognitive impairment are
at one - in - 10 risk of developing dementia within a year — and the risk is markedly higher among those with depression.
For instance, researchers
at IBM Research in Haifa, Israel, are developing a five - minute screening tool that uses voice recordings and computer analysis to identify people with mild
cognitive impairment, a precursor to dementia.
If dozens of human and animal studies published over the past six years are borne out by large clinical trials, nicotine — freed
at last of its noxious host, tobacco, and delivered instead by chewing gum or transdermal patch — may prove to be a weirdly, improbably effective drug for relieving or preventing a variety of neurological disorders, including Parkinson's disease, mild
cognitive impairment (MCI), Tourette's and schizophrenia.
After undergoing the complex process, nine of the 10 participants, who suffered from
cognitive impairment or memory loss associated with Alzheimer's, displayed improvement in memory three to six months into the program — a joint venture between the Mary S. Easton Center for Alzheimer's Disease Research
at UCLA and the Buck Institute for Research on Aging.
«Some astronauts
at risk for
cognitive impairment, animal studies suggest.»
«Regardless if
cognitive impairments precede substance use or vice versa, poorer
cognitive functioning negatively impacts daily life and may cause lack of insight into one's substance use as a source of problems, impeding treatment utilization or decreasing the likelihood of effective treatment,» said senior author Deborah Hasin, PhD, Columbia Mailman School of Public Health professor of Epidemiology and in the Department of Psychiatry
at Columbia University Medical Center.
Older adults with
cognitive and physical
impairments or psychosocial distress are also
at increased risk of elder abuse.
This can result in a serious genetic disease that can cause anemia, neuro -
cognitive impairment, and even early death,» says the study's lead - author, Dr. Jean - Louis Guéant, director of the Inserm unit of Nutrition - Genetics - Environmental Risks
at University of Lorraine and head of the Department of Molecular Medicine and Personalized Therapeutics — National Center of Inborn Errors of Metabolism
at the University Regional Hospital of Nancy.
Yonas E. Geda, M.D. and colleagues
at the Mayo Clinic investigated the relationship between timing of exercise (mid - life / 50 -65 vs. late - life / 70 and above) and risk of new cases of dementia in 280 older adults (median age = 81) with mild
cognitive impairment (MCI) from the Mayo Clinic Study of Aging, and reported on their findings
at AAIC 2014.
People with sleep apnea, for example, a condition in which people repeatedly stop breathing
at night, are
at risk for developing mild
cognitive impairment an average of 10 years earlier than people without the sleep disorder.
«It was the quality of sleep that predicted future
cognitive decline in this study, not the quantity,» said lead author Terri Blackwell, MA, senior statistician
at the California Pacific Medical Center Research Institute (CPMCRI) in San Francisco, Calif. «With the rate of
cognitive impairment increasing and the high prevalence of sleep problems in the elderly, it is important to determine prospective associations with sleep and
cognitive decline.»
«Although this lesion - deficit approach is not widely used, it offers a way to define
impairments in reading in relation to specific
cognitive deficits,» said Dr. Barrett, director of stroke rehabilitation research
at Kessler Foundation.
Until now, scientists haven't understood why about a third of patients who undergo anesthesia and surgery experience some kind of
cognitive impairment — such as memory loss —
at hospital discharge.
«The older African American population is growing
at a rapid pace, and the burden of aging - related
cognitive impairment and Alzheimer's disease will continue to present a tremendous challenge,» said Lisa Barnes, PhD.
A 2010 study by William Jarrold, a
cognitive scientist
at the University of California, Davis, suggests that an automated system that analyzes speech patterns on phone calls can potentially pick up on
cognitive impairment and clinical depression or determine if someone is in the very early stages of Alzheimer's.
In a novel animal study design that mimicked human clinical trials, researchers
at University of California, San Diego School of Medicine report that long - term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of
cognitive impairment in a mouse model of the neurodegenerative condition.
Currently the team has begun a second phase of the project which consists of designing a health intervention programme aimed
at improving
cognitive function and lifestyles related to
cognitive impairment in these patients.
«Early detection of individuals
at high risk of developing memory and thinking problems that we call mild
cognitive impairment (MCI) is crucial because people with MCI are
at a greater risk of developing dementia.
Joe Borelli,
at home with a CPAP machine that helps him breathe, experienced years of fatigue and
cognitive impairment due to an undiagnosed sleep disorder.
«Mild
cognitive impairment has been identified as the transitional stage between normal aging and dementia,» comments M. Arfan Ikram, MD, PhD, a neuroepidemiologist
at Erasmus MC University Medical Center (Rotterdam).
Almost 180 million children across the globe are stunted, a severe, disabling consequence of malnutrition and repeated childhood infections that puts them
at risk for
cognitive impairment and disease.
«Exercising might slow down the rate
at which you would progress from mild
cognitive impairment to dementia,» he says.
The findings, published in the journal Brain, are based on studies of around 60 Alzheimer's patients
at Skåne University Hospital and a control group consisting of 30 people with no
cognitive impairment.
To examine this finding, investigators looked
at whether the hypothesis of
cognitive reserve helps to explain this differential
cognitive impairment following TBI.
«This knowledge may help identify those persons with TBI who need early intervention because they are
at greater risk for
cognitive impairment.
«Although
cognitive status was worse in the TBI group,» said Dr. Sumowski, senior research scientist in Neuropsychology & Neuroscience Research
at Kessler Foundation, «higher education attenuated the negative effect of TBI on
cognitive status, such that persons with higher education were protected against TBI - related
cognitive impairment.»
«This is a simple, common, cheap medicine that may affect an important aspect of
cognitive impairment in older adults, and there's a compelling scientific reason to look
at it.
New research by scientists
at the University of Pittsburgh provides an unprecedented level of resolution and insight into disturbances in cortical GABAergic microcircuits, which are thought to underlie
cognitive impairments in schizophrenia.
Excessive sleepiness can cause
cognitive impairments and put individuals
at a higher risk of motor vehicle crash.
«The next step would be to look
at these same sorts of tasks and see whether or not it could predict individuals who are beginning to show early signs of
cognitive impairment, such as early signs of Alzheimer's disease,» Mewborn said.
They found that those with mild or no
cognitive impairment who had evidence of plaques
at the trial's start worsened to a greater degree on
cognitive tests than those with negative scans.
Of the participants, 69 had normal
cognitive function
at the start of the study, 52 had been recently diagnosed with mild
cognitive impairment, and 31 were diagnosed with Alzheimer's disease.
Most of the players had suffered
at least one concussion during their careers, however, and athletes with three or more concussions were considerably more likely to have been diagnosed with mild
cognitive impairment — a condition that sometimes signals the approach of Alzheimer's disease.
Guskiewicz says the word «mild» is misleading: «This is significant memory
impairment, deteriorating
cognitive function, but not
at the level that they would be classified as being demented.»
A paper published in the December 1999 IEEE Transactions on Neural Systems and Rehabilitation Engineering describes a NavChair Assistive Wheelchair Navigation System (pdf) developed
at the time to reduce the «
cognitive and physical requirements of operating a power wheelchair for people with wide ranging
impairments that limit their access to powered mobility.»