Sentences with phrase «cognitively normal individuals»

«Clinically and cognitively normal individuals with and without AD risk factors, following dietary patterns characterized by high intakes of whole grains, fresh fruits, vegetables, legumes, fish, and low - fat dairy products (which provide higher intakes of vitamin B12, vitamin D, and n - 3 polyunsaturated fatty acids) and by low intakes of refined sugars, French fries, high - fat dairy products, butter, and processed meat, show lower accumulation of Aβ in the brain and higher cerebral glucose metabolism, as evidenced by neuroimaging analysis of gray matter volumes (a marker of brain atrophy), C - Pittsburgh compound B (to measure the accumulation of fibrillar Aβ), and F - fluorodeoxyglucose (to assess brain glucose metabolism.»

A group of 12 individuals with early Alzheimer's were compared to 12 cognitively normal individuals of the same age.

REVEAL - SCAN: Risk Evaluation and and Education of Alzheimer's Disease - the Study of Communicating Amyloid Neuroimaging (RF1 AG047866) is the first multi-site, randomized clinical trial to examine the impact of learning amyloid imaging results in cognitively normal individuals, and its goal is to answer these questions.

Expression studies were conducted using complementary DNA (cDNA) obtained from the parietal lobes of 82 AD cases and 39 cognitively normal individuals (CDR score = 0) obtained through the WU - ADRC Neuropathology Core.

Then, 270 cognitively normal individuals (approximately 25 % African American), aged 65 - 80, will be recruited and randomized to receive their amyloid scan results or not, resulting in subjects whose scan results are disclosed or not and subjects whose scans are amyloid positive or not.

The ADGC is making great strides with your help and the NIA asks that you continue to support them by providing the blood samples from patients and cognitively normal individuals enrolled and receiving the UDS in your Centers.

Not exact matches

Nevertheless, these individuals appear to be cognitively normal.

Through analysis of high - resolution anatomical magnetic resonance imaging of brain volumes, taken three times over the two - year study period, the researchers were able to determine that individuals with MCI or Alzheimer's showed greater losses in gray matter volume in both the basal forebrain and temporal lobe, compared with cognitively normal controls.

Moreover, since amyloid imaging received FDA approval for use in cognitively impaired individuals, our preliminary studies show that clinical investigators want guidance on whether and how to disclose amyloid imaging results, not only to these individuals, but also to cognitively normal older individuals.

Because the brain samples are derived from cognitively normal (CDR score = 0) and demented (CDR score > 0.5) individuals, we first tested whether there was an association between mRNA levels and CDR score.