To better understand the formation of metastases in pancreatic cancer, Christine Iacobuzio - Donahue, M.D., Ph.D., professor of pathology at Memorial Sloan Kettering Cancer Center,
collected tumor samples from eight patients with the most common form of pancreatic cancer (pancreatic ductal adenocarcinoma) immediately after their deaths.
The study found that it's now feasible in dogs to
collect a tumor sample and perform molecular profiling in less than a week's time, a clinically practical window.
Not exact matches
Users simply
collect a blood
sample from a patient, feed it into the device, and retrieve any purified
tumor cells a few hours later.
Researchers said the importance of
collecting tissue
samples from recurrent
tumors will grow as more targeted therapies become available.
Searching for T cells that had infiltrated the
tumors, they
collected as many as 50 T cell
samples from a single
tumor; next, the team tested each batch of T cells against other
tumor samples from the same patient.
When possible, scientists will also
collect and store other biological specimens such as leftover
tumor or bone marrow
samples.
Caris, under the guidance of Baker, provided the tissue and ran the molecular profiling on solid
tumor samples collected from across the United States.
The ViroChip microarray [2], [3], [44], [45] was used to screen RNA
samples isolated from prostate
tumors collected prospectively from 39 individuals, of which 16 individuals were genotyped as harboring the R462Q RNAse L mutation (QQ), 10 individuals were heterozygous cases (RQ), and 13 were wild - type cases (RR).
The team will capture the
tumor samples» genomic and transcriptomic data as well as the clinical outcomes and drug responses of each patient, starting with 842 participants and the already -
collected tumor biopsies from 3,000
tumor regions among them.
If your dog is female, your vet can use a cytoscope — a tiny camera threaded into the bladder — to view the
tumor or
collect a
sample for biopsy.
Diagnosis of oral SCC requires a biopsy of the
tumor with the cat under general anesthesia so that a good
sample of the
tumor can be
collected.
Tumor samples may ultimately be
collected from cats undergoing surgical biopsies and formalin fixed.
Next, a biopsy or tissue
sample of the
tumors, or any excessive fluids that have
collected in body cavities, may be taken and analyzed.
To avoid the risk of
tumor seeding (spillage of
tumor cell clusters and their subsequent growth at a site adjacent to the original
tumor) through cystosyntesis (a procedure in which needle is inserted into the urinary bladder of an animal through the abdomen and a
sample of urine is removed), urine may be
collected by free catch or catheterization.
Radiographs of the chest and back will be analyzed to screen for
tumors or other damage to the skeletal system, and a
sample of the fluid surrounding the spinal cord may be
collected for analysis.
As part of our mission to improve the health and longevity of our Berners, the Berner - Garde Foundation (BGF) and Michigan State University (MSU), with support from the Bernese Mountain Dog Club of America (BMDCA), have established a Repository that
collects, stores and maintains DNA and
tumor tissue
samples from Bernese Mountain Dogs.