Researchers have developed an array of mouse models to help scientists understand a whole
collection of human diseases.
Not exact matches
They have the opportunity to be exposed to a wide variety
of clinical and patient - oriented research, from Phase I, II, and III trials to
collection of samples and clinical data used to identify genetic variation that leads to
human disease.
BETHESDA, Md., Wed., Oct. 5, 2005 - The National Institutes
of Health (NIH) today announced contracts that will give researchers unprecedented access to two private
collections of knockout mice, providing valuable models for the study
of human disease and laying the groundwork for a public, genome - wide library
of knockout mice.
Biomedcode is a Contract Research Organisation (CRO) providing full preclinical drug evaluation services to the pharmaceutical industry using a unique
collection of mouse models
of human inflammatory
diseases.
Potential projects include identifying common pathways that modify retinal degenerative
disease from a large
collection of actively maintained mouse models; determining molecular networks implicated in pathological disruption
of the retinal pigment epithelium; identifying molecular pathways that regulate postnatal ocular growth; and using mouse models to assess the pathogenic role
of gene variants that increase the risk
of age - related macular degeneration as identified by
human genome - wide association studies.
That
collection of organisms strongly influences
human health by, for example, producing anti-inflammatory factors, inactivating drugs, and altering the course
of disease.