Sentences with phrase «colon cancer cell lines»

Scientists studied the effect of GSE on various stages of colon cancer cell lines, ranging from Stage 1 to Stage IV.

In the current studies, the researchers used a transplanted colon cancer cell line.

For the time course study, cells were treated with 20 μM of EGCG for 12, 24, 48, 72, or 144 h. Human colon cancer cell line HT - 29 and prostate cancer cell line PC3 were obtained from American Type Culture Collection (Manassas, VA), and were grown in McCoy's 5A and RPMI 1640 containing 10 % fetal bovine serum, respectively.

In the present work, our observations led us to conclude that inhibition of TRF2 abrogates the formation and maintenance of the spheroidal phenotype and loss of TRF2 results in down regulation of CSC characteristics when exposed to DNA damaging environment in HCT116 colon cancer cell line.

The study builds on previous findings suggesting that AIM2 limits cancer cell growth in colon cancer cell lines, Wilson said, as well as on a clinical report of poor prognosis in colon cancer patients with low or missing AIM2 levels.

«In the study, using human colon cancer cell lines, we showed that the growth of cancer cells can be largely prevented using a combination of both drugs in a petri dish as well as in mouse models,» said Srivastava.

So far, Menendez and his colleagues have discovered the fatty acid cuts the expression of the gene in ovarian, stomach, and colon cancer cell lines.

Specifically, we have demonstrated that histone deacetylases (HDACs) and bromodomain - containing proteins are required for colon cancer cell growth, and have demonstrated that inhibitors of these enzymes induce growth arrest and apoptosis in colon cancer cell lines.

Furthermore, using a phospho - tyrosine [Y] 474 (in - house generated) and a phospho - serine [S] 176 (Cell Signaling, Inc., Danvers, MA) RIPK2 antibodies, we confirmed that active RIPK2 is recognized by these antibodies upon activation with MDP treatment in 293HEK fibroblast and HCT116 colon cancer epithelial cells (Fig. 3E, left panel) and detection of constitutively active RIPK2 in the colon cancer cell line SW480 (Fig. 3E, right panel).

Editing GalNAc - T6 out of a colon cancer cell line changed its growth form to one more closely resembling healthy colon tissue.

(Source) Another study evaluated the effects of avocado on gastrointestinal cancers, and found avocado extract to inhibit the growth of esophageal squamous cell and colon cancer cell lines.