Sentences with phrase «colon cancer organoids»
The Hubrecht lab is also involved in two trials to assess whether colon cancer organoids grown from individual patients can predict drug response.
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To demonstrate that ability, the MIT team delivered organoids with a mutated form of the APC gene, which is the cancer - initiating mutation in 80 percent of colon cancer patients.
In the new paper, the researchers used CRISPR to introduce cancer - causing mutations into the organoids and then delivered them via colonoscopy to the colon, where they attached to the lining and formed tumors.
The HUB also maintains large biobanks of colon -, breast -, lung - and pancreas cancer organoids, accessible by academia and industry.