Dallosso AR, Øster, B, Greenhough A, Thorsen K, Curry TJ, Owen C, Hancock AL, Szemes M, Paraskeva C, Frank M, Andersen CL, Malik K. Long - range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of
colorectal tumorigenesis through modulation of oncogenic pathways.
Not exact matches
«We found that AIM2 inhibits
tumorigenesis in multiple animal models of
colorectal cancer by restricting the pro-survival signaling molecule, Akt, which is commonly hyperactive in many human cancers.»
The
tumorigenesis mechanisms of
colorectal cancer have been widely studied at a molecular level.
The paper, Redundant Innate and Adaptive Sources of IL17 Production Drive Colon
Tumorigenesis, http://cancerres.aacrjournals.org/content/76/8/2115, April 2016 found that
colorectal cancers associated with B. fragilis could be suppressed, not just by eradicating the microorganism, BUT ALSO BY REDUCING INFLAMMATION.