Sentences with phrase «combination antifungal therapy»

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«Our research adds weight to the idea that effective antifungal drugs can target even those mitochondrial proteins that are highly conserved in humans and fungi, and that this could be a way to make a broad spectrum antifungal combination therapy that would be less susceptible to resistance,» says Benjamin Vincent, a former graduate student in Whitehead Member Susan Lindquist's lab who is now a scientist at Yumanity Therapeutics.
By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with fluconazole, one of today's most commonly prescribed fungal infection treatments.
Dogs with fungal discospondylitis may require lifelong treatment with antifungal drugs.3 In cases of Brucella - positive dogs, combination therapy consisting of doxycycline and an aminoglycoside is indicated.5 Corticosteroids are generally contraindicated because of possible impairment of the immune system.3
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