Soft Tissue Sarcoma Opportunity: in both our monotherapy single arm Phase 1 and
combination randomized Phase 2 studies, we are focusing on two types of sarcoma where we believe there is significant unmet need: synovial sarcoma and Myxoid round cell liposarcoma.
Not exact matches
In a
randomized,
phase 2 multi-center clinical study, led by Manisha Shah, MD of The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone compared with the same drug given in
combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf mutations.
Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a
Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC
14255: STAT3 Signaling During Chemo - Radiation for Squamous Cell Carcinoma of the Head and Neck 14340: A
Phase II,
Randomized, Open - Label, Multi-Center, Global Study of MEDI4736 Monotherapy, Tremelimumab Monotherapy, and MEDI4736 in
Combination with Tremelimumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN) 14258:
Randomized Phase II and
Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)
Phase 2
Randomized, Double - Blinded, Controlled Study of Tucatinib vs. Placebo in
Combination with Capecitabine and Trastuzumab in Patients with Pretreated Unresectable Locally Advanced or Metastatic HER2 + Breast Carcinoma
A
Randomized Phase 2 Study of Atezolizumab in
Combination with Cobimetinib Versus Atezolizumab Monotherapy in Participants with Unresectable Cholangiocarcinoma
A
Phase III, Multicenter,
Randomized, Placebo - Controlled Study of Atezolizumab (ANTI − PD - L1 Antibody) as Monotherapy and in
Combination with Platinum - Based Chemotherapy in Patients with Untreated Locally Advanced or Metastatic Urothelial Carcinoma
A
Phase I - II
Randomized Trial of a
Combination of Nintedanib / Placebo in
Combination with Induction Chemotherapy for Patients with Refractory or First Relapse Acute Myeloid Leukemia
A
Randomized Phase 2 Study of Cediranib in
Combination with Olaparib versus Olaparib Alone in Men with Metastatic Castration Resistant Prostate Cancer
He is the Principal Investigator of international
Phase - II,
randomized trial of Chimeric 14.18 or Temsirolimus in
combination with Irinotecan / Temozolomide through Children's Oncology Group (COG).
Status: G100 is being studied in a fully - enrolled
randomized Phase 2 trial in patients with follicular non-Hodgkin Lymphoma (FL) in
combination with local radiation and Merck's anti-PD-1 agent, pembrolizumab, pursuant to a clinical collaboration with Merck.
Ludwig, M., Finas, A., Katalinic, A., Strik, D., Kowalcek, I., Schwartz, P., Felberbaum, R., Kupker, W., Schopper, B., Al - Hasani, S., and Diedrich, K. Prospective,
randomized study to evaluate the success rates using hCG, vaginal progesterone or a
combination of both for luteal
phase support.
A prospective
randomized study comparing hCG, vaginalmicronized porgesterone and a
combination regimen for luteal
phase support in an in - vitro fertilization programme [abstract].