Professor Siddiqui and his team identified multiple biological «micro-clusters» which means that there are different
combinations of active genes in each of the reported subtypes of asthma.
The whole process is reminiscent of trial - and - error learning in which each cell explores — at its own rhythm and independently of cell division — different molecular possibilities (i.e. different genes turned on or off) before reaching a stable
combination of active genes and the corresponding morphology.
Not exact matches
In some
genes, different
combinations of exons can become
active at different times, and each
combination yields a different protein.
Each cell's particular
combination of active and silent
genes helps determine what kind
of tissue it will give rise to — liver, heart, brain, and so on.
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