Sentences with phrase «combine approaches targeting»

We propose that interventions that combine approaches targeting the inappropriate behaviors of children with ADHD with approaches to increase the inclusiveness of the peer group may be most likely to normalize social functioning in ADHD populations.

Previous work has suggested that a combined approach targeting HER2, ER, and RB1 may improve outcomes.

Not exact matches

The decision about whether to stick with free listings, enter the PFP universe, or combine the approaches depends on your budget, your competitors» strategies, and a sense for how your target audience will respond (many users dislike paid placements, especially those that look too much like free search results).

We believe that our own Responsible Sourcing Platform, which combines in - house codes and guidelines, capacity - building teams for key commodities and suppliers, NGO and industry partnerships and third - party certifications, offers a more targeted approach than certification alone.»

We prefer to have a simplified, yet targeted approach combining actives in one formulation to deliver results.

Researchers also found that targeted biopsy was better able to predict whether the disease was low - or intermediate risk than standard biopsy or the two approaches combined.

Physicians in the recent trial used a targeted approach to evaluate prostate cancer that combines MR imaging and transrectal ultrasound fusion guided prostate biopsy.

Researchers at Penn State have combined the two approaches by taking biodegradable polymer nanoparticles encapsulated with cancer - fighting drugs and incorporating them into immune cells to create a smart, targeted system to attack cancers of specific types.

«Strikingly, both primary and metastatic castration - resistant prostate cancer responded to a combined checkpoint blockade and MDSC targeted therapeutic approach,» said DePinho.

By using «gemcitabine» chemotherapy to target cancer cells, and a form of vitamin A to target the surrounding stromal cells, the combined approach led to a reduction in cancer cell proliferation and invasion.

When combined with the older antivirals, PB1 - targeted drugs could drastically reduce the spread of resistance, making the approach of the annual flu season a little less worrisome for everyone.

Indeed, their combined phenotypic screening and target - identification approach enabled them to quickly discover, characterize and carry out preclinical tests of a potential new drug for obesity - linked diabetes: a complex metabolic disorder that affects 347 million people worldwide.

For the first time, their study combines the strengths of simulations based on integrated energy - economy - climate models that estimate cost - optimal long - term strategies to meet climate targets with life cycle assessment approaches.

Such methods are often combined with missing feature approaches, which use a single - talker model to recognize the speech based on regions of the spectrogram that are dominated by the target talker, while ignoring areas dominated by other sounds.

In an effort to combine the respective advantages of the AAV and CRISPR - based approaches, several groups have recently worked to enhance the efficiency of AAV - based gene editing via the introduction of a double strand break by using a targeted nuclease.

By combining SNP - targeting allele - specific silencing and gain - of - function approaches, we showed that a 46 - glutamine expansion in human HTT was sufficient for a dominant - negative effect on spindle orientation and changes in the distribution within the spindle pole and the cell cortex of dynein, p150Glued and NuMA in neural cells.

Combining the value of structure - guided Medicinal Chemistry with the confidence that the starting hit achieves its disease - relevant effect through interaction with the target, is an especially powerful approach.

These questions will be addressed by combining unbiased «omics» - approaches (i.e. genomics, transcriptomics, and proteomics) and a targeted genetic analysis with both superresolution live - cell imaging and electron microscopy of nanotube - forming cells.

«We are pleased to have an opportunity to combine our know - how and Merck's complementary approach to genetics and global leadership in the development of innovative therapeutics, to bring into development a series of novel, population - validated targets that may lead to a qualitative leap in our approach to treating obesity.»

The resulting data are being combined in a systems biology approach with high - resolution clinical phenotyping and findings obtained with a large array of established and novel in vitro, ex vivo and in vivo disease models to identify disease - associated genetic variants, disease - defining molecular signatures, and potential targets for therapeutic intervention.

Engineering of a target site - specific recombinase by a combined evolution - and structure - guided approach.

We use a combined experimental and computational approach to predict whether sequence motifs and / or pre-existing histone modifications direct the recruitment of histone methyltransferases to their targets.

Abi - Ghanem, J.; Chusainow, J.; Karimova, M.; Spiegel, C.; Hofmann - Sieber, H.; Hauber, J.; Buchholz, F.; Pisabarro, M. T. Engineering of a target site - specific recombinase by a combined evolution - and structure - guided approach.

She combines a sensible nutritional approach that restores the body's pH, insulin sensitivity, gut microbiome, and antioxidant defence, with an intelligent supplements protocol that targets neurotransmitters deficiencies, restores nutrient deficiencies, repairs the gut lining, and modulates hormonal responses.

When combined with a healthy reduced calorie diet and exercise plan ‡, Maximum Strength 3 - in - 1 Carb Blocker ® provides a targeted approach to helping you achieve your weight loss goals.

NuGospel is combining the traditional Faith - based production approach with new media distribution format «Social RadioTV» targeting Urban Millennials communities domestically and internationally.

Our investment approach combines low - cost, tax - efficient indexed investment focus with targeted active management strategies and sophisticated risk - mitigation and income - enhancement techniques to maximize client returns at any risk level.

This is the «bottom up» or «soft» approach described by Andrew Revkin at the start of the summit, although the combined commitments almost certainly won't be enough to keep the planet below the politically agreed target of 2 degrees Celsius average warming.

The ultimate political question seems to be whether there is greater (geographic and sectoral) political support for the Waxman - Markey (H.R. 2454) approach of substantial free allocations and targeted use of auction revenue, or if there is greater (populist) political support for the full auction combined with lump - sum rebate which characterizes the «cap - and - dividend» approach.

About you: * You will have ability to demonstrate success in a sales based role (12 months +) will be a huge advantage, combined with commercial awareness and a proactive approach to achieving targets * You will be self - motivated, target driven and determined to use your sales experience to secure a long - term career as a Recruitment Consultant.

Intervention characteristics associated with more effective outcomes: promoting positive mental health rather than the prevention of mental illness; continuous and long term; whole school approach, focusing on school climate and environment rather than on individual change; opportunities for practice in range of contexts, addressed self - concept, self - esteem and coping skills; combining universal and targeted programmes