Sentences with phrase «combined mouse studies»

Not exact matches

While study results indicated that combining capsaicin with the chemicals «might promote cancer cell survival,» the report clearly stated that the control group of mice treated only with capsaicin ``... did not induce any skin tumors...» In addition, the study repeatedly cited other research studies in which the anti-cancer properties of capsaicin were solidly demonstrated.

Now, in a new study using laboratory - grown cells and mice, Johns Hopkins scientists report that a method they used to track metabolic pathways heavily favored by cancer cells provides scientific evidence for combining anti-cancer drugs, including one in a nanoparticle format developed at Johns Hopkins, that specifically target those pathways.

In March 2016, Penn researchers published a study in Blood that showed long - term ibrutinib treatment reverses the dysfunction of T cells in CLL and that combining CAR therapy with ibrutinib enhanced engineered T cell proliferation in mice.

The new study — published October 18, 2016 in the journal Molecular Psychiatry — combined genetic analysis of more than 9,000 human psychiatric patients with brain imaging, electrophysiology, and pharmacological experiments in mutant mice to suggest that mutations in the gene DIXDC1 may act as a general risk factor for psychiatric disease by interfering with the way the brain regulates connections between neurons.

Combined with rapamycin, metformin (teal) boosted median life span in both sexes about 23 percent, but the result wasn't statistically different from life span boosts in mice given rapamycin alone in previous studies.

Using an approach combining chemistry and genetic analyses, the researchers studied normal and genetically altered mice.

For this study, Jabri and colleagues combined insights and data from celiac disease patients who had been cared for at the University of Chicago's Celiac Disease Center with experiments using a mouse model of the disease developed in her lab.

Taking advantage of fly genetics The research will combine the strength of the fly system (animals that are short lived but complex enough to model regenerative activity in vertebrates) with genetic studies in mice to understand the role of mTOR signaling in maintaining the health of adult stem cells in both species.

Combined with previously published studies, our data indicate that infection with all three major North American T. gondii clonal lineages results in loss of innate, hard - wired aversion to feline predator urine in mice.

Lack of oxygen during pregnancy combined with high salt intake in later life can damage vascular function in the offspring of mice, according to a study published today in The Journal of Physiology.

He later combined it with studies on chromatin, tissue specific gene expression and mouse models for human diseases including Type II diabetes, polycystic kidney disease as well as cancer.

In this study, we established mouse iPS cell lines from NPCs of neonatal EGFP - transgenic mice on the HFF feeder cells via viral transduction of 4 factors, combined with application of 2i.

The metabolic analysis of the mice could be combined with clinical assessments, by performing biochemical analysis in blood, plasma, urine and tissues (i.e, lipid and cholesterol content, glycogen content...) and by performing autopsy of the animal at the end of phenotyping study with several tissue collections (i.e, histology, mRNA anlaysis, protein analysis...).

Whether or not other genetic manipulations combined with the loss of DJ - 1 lead to SNpc degeneration in mice should be the subject of future studies.

Mice given astaxanthin were found to have accelerated body fat reduction (i.e., «fat burning») when combined with exercise, as compared to exercise alone in a 2007 study by Aoi et al. 9 Aoi reports the carotenoid seems to exert this effect by protecting the function of a lipid transport enzyme on the membrane of mitochondria that «fuels» energy production.

There is another study in mice that tested the ketogenic diet with or without hyperbaric oxygen therapy and compared to the standard diet, the ketogenic diet increased mean survival time by 56 percent and that number increased to 78 percent when it was combined with hyperbaric oxygen.