They also investigated a new strategy to significantly inhibit glioma growth by rationally
combining gemcitabine and MK - 8776, a cell cycle checkpoint inhibitor.
They will follow this approach to design a novel treatment plan by rationally
combining gemcitabine with cell cycle checkpoint inhibitor, oxygen - enrich gas inhalation, and radiotherapy to significantly inhibit the growth of aggressive glioma.
«Our phase 1 trial
combines gemcitabine with two novel cancer immunotherapies — a regimen that has not been tried before,» said Venepalli, a member of the UI Cancer Center.
Not exact matches
By using «
gemcitabine» chemotherapy to target cancer cells, and a form of vitamin A to target the surrounding stromal cells, the
combined approach led to a reduction in cancer cell proliferation and invasion.
The findings suggest that therapies
combining these microRNAs and
gemcitabine could improve our ability to treat pancreatic cancer, and measurement of microRNA levels could also provide a guide to the prognosis in such cases.
When pemetrexed and
gemcitabine were
combined with two chemotherapy drugs currently used to treat pediatric medulloblastoma, the mice lived even longer.
This result therefore indicates that
combined rituximab and
gemcitabine could be an alternative approach in patients with posttransplant lymphoproliferative disease.
In - vivo treatments of xenografted tumors showed significant tumor growth inhibition induced either by rituximab or
gemcitabine alone and an impressive efficacy of
combined treatment.