A classical ketogenic diet — with a staggering 70 - 90 percent of total calories
coming from fat — might not be necessary.51 Classical ketogenic diets restrict
protein as well as carbohydrate, since 48 - 58 percent of the amino acids in dietary
proteins can be glucogenic,
thereby undermining the purpose of a diet intended to generate a high amount of ketones and limit glucose as much as possible.46 As therapy for AD, however, simply lowering carbohydrate intake to a point where some ketones are generated and hyperinsulinemia is corrected could have positive effects just by easing the metabolic burden on the brain.
A number of other dietary factors can impair the production of anti-inflammatory hormones,
thereby increasing the inflammatory ones: low levels of vitamins B6, C, E, niacin, and the minerals magnesium, calcium, and zinc (these should
come from a healthy diet); trans fat; low
protein intake; excess stress; and aging, which increases the risk of more inflammatory chemicals.