By screening
commercially available drugs currently being used for other diseases, researchers found vorinostat to be an effective anti-seizure drug in zebrafish and mouse models.
Monk also said that Gpr56 belongs to a large class of cell receptors that are common targets for many
commercially available drugs, making the protein attractive for further research.
«There are currently virtually no treatments for dilated cardiomyopathy targeted to genetic changes, so the finding that
commercially available drugs may be effective for patients with childhood - onset, RAF1 - induced DCM is a remarkable advance,» said Bruce Gelb, MD, Director and Gogel Family Professor of the Mindich Child Health and Development Institute at Mount Sinai and senior author.
«This research is highly significant as it implies that
a commercially available drug, amphotericin B, which has never been used before for patients with gliomas, may be a novel treatment to consider in future trials of patients with this frequently lethal cancer,» says Dr. Rutka.
He cautioned, however, that further studies must be done to confirm this potential, and
a commercially available drug is many years off.
Not exact matches
The U.S. Food and
Drug Administration (FDA) sets and enforces specific limits on safe levels of key ingredients, such as certain vitamins and minerals, for all
commercially available infant formulas.
Drugs in the Valium class and painkillers have a reversing agent that's
commercially available.
Although more trials are needed before flibanserin could become
available commercially, it shows promise as the first
drug demonstrated to treat low libido in women — the most common sexual problem in females — by targeting the brain.
The study used a well - known line of pancreatic cancer cells (AsPC - 1) in the laboratory and assessed how well this grew when treated with either the chemotherapy
drug gemcitabine or different levels of
commercially available chokeberry extract alone, and when treated with a combination of gemcitabine and chokeberry extract.
The dual -
drug combination will likely cost even more, which has prompted outrage from physicians and patient advocates alike, as well as plans from insurers to ration the combination when it becomes
commercially available.
It has assembled an extensive library of
commercially available compounds and natural products that can be screened in seconds using its proprietary Avalanche tool to jumpstart its
drug discovery programs.
Commercially available subsets of the ZINC (15,868,179 compounds) and MolPort (7,241,662 compounds) databases were screened using the lead
drug ponatinib as a reference.
One case study found that when a patient submitted to the ER ingested a
commercially available diet pills containing the appetite suppressant phenylpropanolamine, the inhibition of prostaglandins caused by the
drug resulted in extreme hypertension (19).
Compounding is generally regulated by individual states with varying levels of oversight; however, there is one
commercially available form of potassium bromide (K - BroVet) that is prepared by a
drug manufacturer licensed by the FDA and which adheres to FDA manufacturing standards.
Milbemycin Oxime prevents and treats roundworms, hookworms, and whipworms and is
commercially available in
drugs such as Interceptor and Sentinel.
These types of pharmacies typically produce unique combinations or dosages of
drugs that aren't
available commercially.