Sentences with phrase «common disease studies»

There * are * large sample collections for common disease studies that have been banked for the last decade or more.

Not exact matches

But it has been disappointing in that the kind of genetic variation it detects has turned out to explain surprisingly little of the genetic links to most diseases... One issue of debate among researchers is whether, despite the prospect of diminishing returns, to continue with the genomewide studies, which cost many millions of dollars apiece, or switch to a new approach like decoding the entire genomes of individual patients.The unexpected impasse also affects companies that offer personal genomic information and that had assumed they could inform customers of their genetic risk for common diseases, based on researchers» discoveries...

Recent studies even show that plaque that builds up in the brain from unhealthy levels of cholesterol may be one of the most common reasons for Alzheimer's disease.

Most studies have revealed protective effects of breastfeeding on common infections in the first 8 to12 months of life.8, 27,29,30 One study, which distinguished between infectious diseases until and from the age of 6 months, revealed results similar to those from our study.24 Although the authors used exclusive breastfeeding for 3 months as the reference group, exclusive breastfeeding for 6 months reduced the risk of gastrointestinal tract infections between the ages of 3 and 6 months but not between the ages of 6 and 12 months.24 We can not explain why breastfeeding duration was only associated with lower risks of lower respiratory tract infection from 7 to 12 months.

However, the organization also called for more research regarding the benefits of 6 vs 4 months of exclusive breastfeeding.25 Thus far, several studies in industrialized countries revealed that a shorter duration of breastfeeding increases the risk of common infectious diseases, such as respiratory and gastrointestinal tract infections.8, 19,24,26, — , 32 However, in these studies, various definitions of the exclusiveness of breastfeeding were used24, 27,28,30 or the combination of duration and exclusiveness of breastfeeding was not taken into account.8, 31

Usually, state health departments rely on standard questionnaires to find a common culprit for a cluster of reported illnesses, says Samuel Crowe, an epidemiologist at the Centers for Disease Control and Prevention in Atlanta, who led the study.

Severe chronic periodontitis is the sixth most common medical condition according to the Global Burden of Disease Study 2014.

Professor Gallagher, from the University's Institute of Ageing and Chronic Disease concluded: «Studying a rare illness like alkaptonuria is a worthwhile project in itself, but it can also help with new insights into much more common diseases.

Higher concentrations of bisphenol A — a common ingredient in plastics found in products ranging from polyester to water bottles — have been linked to heart disease, according to a new follow - up study.

What impact they may have had is now only a guess, but this study revealed that these cells were less common in the brains of women who had Alzheimer's disease, suggesting they may be related to the health of the brain.

One research group needed 20,000 samples for a study of the epidemiology of common diseases.

Former studies have already proven that smoking during pregnancy can harm the unborn child: Newborns from smoking mothers have shown low birth weights and impaired lung functions; later on in life respiratory diseases, diabetes type II, asthma or cardiovascular diseases were also more common.

«The disease was known to be common in racehorses, but not as widespread as this study reveals,» said Caswell.

In the second study, Dr. McCoy and colleagues demonstrated the application of this new method to examine the association between symptom dimensions and common genetic variation in psychiatric disease.

That's when a women's health study, stopped early after a data review, published results linking a common hormone therapy to an increased risk of breast cancer, heart disease, stroke and blood clots.

Professor Julian Walters, from the Department of Medicine at Imperial College London, who led the study, said: «Many doctors are totally unaware of bile acid diarrhea, but it's more common than Crohn's disease and ulcerative colitis.

The study, the largest of its kind in the world, compared the health of Deaf people with the hearing population and found that Deaf adults have high levels of risk factors for common conditions, such as heart disease, high blood pressure and diabetes.

«A common fallacy is that schizophrenia can be treated as a single disease,» says NYU Langone psychiatrist and lead study author Dolores Malaspina, MD. «Our biologically driven study begins to answer longstanding questions in the field about why any two people diagnosed with schizophrenia may have drastically different symptoms.

A new study published in the Journal of the American Medical Association found depressed patients with chronic kidney disease did not benefit from a common antidepressant.

The study supports the «hygiene hypothesis,» which contends that such auto - immune diseases are more common in the developed world where the prevalence of antibiotics and antibacterials reduce children's exposure to microbes.

«Dementia, including the most common form Alzheimer's Disease, and related neurodegenerative conditions are dramatically rising in frequency as people live longer and our population ages,» says study lead Professor Robert Richards, from the University of Adelaide's School of Biological Sciences.

For the study, researchers measured the level of calcium in the coronary arteries during stress testing using two common diagnostic tests — positron emission tomography, or PET, and computed tomography, or CT — to determine a patient's risk of heart disease.

ROCKVILLE, MARYLAND — The first major epidemiological study of bisphenol A, a common ingredient in baby bottles and drink containers, suggests that relatively higher doses of the chemical double the risk of diabetes and cardiovascular disease.

A study in rats suggests that exposure to environmental toxins could be contributing to an inherited vulnerability to common diseases like breast cancer and high cholesterol.

«We see that two completely different disease entities share a common pathogenic mechanism,» said George Hajishengallis, a professor of microbiology in Penn's School of Dental Medicine and an author on the study.

«Common pesticides kill amphibian parasites, study finds: Disease outcome in amphibians may be influenced.»

«We were surprised to find so many similarities between these two diseases, but most striking was that some of these common signatures are shared with other conditions like diabetic retinopathy and age - related macular degeneration,» said William A. Beltran, senior author on the study, an associate professor of ophthalmology in Penn Vet's Department of Clinical Sciences and Advanced Medicine and director of the Division of Experimental Retinal Therapies.

«The circumstances of the Dutch Hunger Winter of 1944 - 1945, with civilian starvation caused by the conditions of World War II, offer a unique opportunity to study the possible fetal origins of common diseases and adult health and critical periods in gestation,» said L.H. Lumey, MD, PhD, Mailman School associate professor of Epidemiology and lead author.

«This landmark study draws the conclusion in pre-clinical animal studies that stem cell therapy for disc degenerative disease might be a potentially effective treatment for the very common condition that affects people's quality of life and productivity,» said the senior author, Wenchun Qu, MD, PhD, of the Mayo Clinic in Rochester, Minn..

Finding funding for in - depth epidemiological studies of kidney cancer can be difficult, however, because the disease is not as common as other cancers, and not as deadly as gliomas, or liver or pancreatic cancer.

Scientists studying the commonest of the diseases in the group, scrapie in sheep, concluded decades ago that no virus or bacterium could be involved because infectious material appeared to contain no DNA.

«The genome contains all the information needed to build and maintain an organism, but it also holds the details of an individual's risk of developing common diseases such as diabetes, heart disease and cancer,» says study lead - author Arttu Jolma, doctoral student at the Department of Biosciences and Nutrition.

And large, genome - wide studies searching for genetic underpinnings for more common diseases, such as lung cancer or autism, have pointed to the nether regions of the genome between the protein - producing genes — areas that were often thought to contain «junk» DNA that was not part of the pantheon of known genes.

«Activation of these cell receptors appear to prevent brain cells from cleaning out the trash — the toxic buildup of proteins, such as alpha - synuclein, tau and amyloid, common in neurodegenerative diseases,» says the study's senior author, neurologist Charbel Moussa, MBBS, PhD, director of Georgetown's Laboratory for Dementia and Parkinsonism, and scientific and clinical research director of the GUMC Translational Neurotherapeutics Program.

Principal investigator for the study and a professor at UNICAMP's Medical School (FCM - UNICAMP), José Dirceu Ribeiro recalls that bronchiolitis is the most common disease during the first year of life, and also the leading cause of hospitalization during this period of infancy worldwide.

«Recent studies in Africa and South Asia by people using sophisticated techniques show this organism is a very common, underappreciated cause of diarrheal disease in underresourced countries.»

Published September 15 in Genome Biology, the study relied on new software for researchers that identifies connections between seemingly unrelated human diseases and traits through the tiny, risk - conferring genetic variations they have in common.

«Inherited, rare skin disease informs treatment of common hair disorders, study finds.»

Pregnant women with mid to high levels of antibodies common in patients with celiac disease are at risk for having babies with reduced fetal weight and birth weight, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association.

This is also the first study to date suggesting the disease is a milder form of the more common and serious disorder.»

Women diagnosed with polycystic ovary syndrome — the most common hormone disorder in women of reproductive age — face a heightened risk of developing heart disease, diabetes, mental health conditions, reproductive disorders and cancer of the lining of the uterus than healthy women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

Among 277 survivors studied in March and April of this year, complications were common, said Dr. Sharmistha Mishra, the senior author of the paper and an infectious diseases physician at St. Michael's Hospital in Toronto.

Their studies indicate that the two conditions common in sickle cell disease, dramatically increase red blood cells» adhesion to the lining of blood vessels walls and the debilitating pain crises that can result.

One difficulty in studying the genetics of common mental illnesses is that they are generally caused by environmental factors in combination with multiple gene variants, any one of which usually could not by itself cause disease.

Study of the genetic and environmental risk factors for atherosclerosis in ancient people may offer insights into this common modern disease.»

Further study of the genetic and environmental risk factors for atherosclerosis in ancient people may offer insights into this common modern disease.»

For the near term, groups known as accelerated development and introduction plans (ADIPs) have studied the possibility of more rapidly introducing new vaccines for rotavirus, a common diarrheal disease, and pneumococcus, a bacterium that causes pneumonia.

That's the claim of a new study, which finds increases in metabolic disease and intestinal inflammation in mice fed two common emulsifiers used in processed food.

«This is how we can start thinking about precision medicine in action,» said the study's senior author, Alice S. Chen - Plotkin, MD, an assistant professor of neurology at Penn. «We found that a relatively common genetic variation can both serve as a biomarker for and influence the disease course of Parkinson's patients.

Bhandari studies Bronchopulmonary Dysplasia (BPD), the most common chronic lung disease in premature infants.