The researchers used gene - sequencing technology to determine the most
common gene alterations associated with the cancers and then used their test to find and extract from the fluid cancer the DNA specific to each cancer.
Not exact matches
An abnormal
gene created by the fusion of ETV6 and the RUNX1
gene is one of the most
common alterations in childhood ALL and is found in the leukemic cells of 20 to 25 percent of pediatric ALL.
Some of the
common genetic
alterations identified in the study were gains and losses in chromosome 8, as well as cell proliferation and cell - cycle progression — key mechanisms of cancer caused by genetic
alterations — linked to the
genes AURKA, AURKB and FOXM1.
Several
common single -
gene alterations have been observed in glioblastoma.
Genetic tests, such as those used in this study, can detect
common variants of
genes associated with modest
alterations in the chances of developing particular diseases.
A study led by St. Jude Children's Research Hospital shows epigenetic changes that turn
genes on and off are as unique as
alterations in DNA and may be as important in causing the most
common childhood cancer