Sentences with phrase «common neoplasms»

Not exact matches

From a u-CT scan and an X-ray, researchers identified a fibrous dysplastic neoplasm — today, the most common form of benign bone tumor in humans — located on a Neandertal left rib fragment that measured 30 mm (4 1/2 inches) long.

According to the American Cancer Society, the most common pediatric neoplasms are leukemia, brain and spinal cord tumors, neuroblastomas, Wilms tumors, and lymphoma, including both Hodgkin and non-Hodgkin.

Plasma cell neoplasms are most common in people who are middle aged or older.

In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.10

The most common cause of obstruction is a urethral plug, which consists of mineral crystals (e.g., struvite, calcium oxalate), white blood cells, red blood cells, protein (mucus), and epithelial cells.5 The underlying cause of urethral plugs is unknown; however, plugs have been linked to struvite crystalluria — suggesting that diet may play a role — and idiopathic cystitis.6 Other causes of urethral obstruction include urethral edema and spasm associated with lower urinary tract inflammation and pain.7 Uroliths, neoplasms, and urethral strictures can also lead to urethral obstruction; however, they are reported less frequently than other causes.5

Ceruminous gland adenomas or adenocarcinomas are the most common otic neoplasms.

Primary bone tumors (neoplasms) are common in dogs.

Neoplasms inside the abdomen are common.

In situations where a neoplasm is not present [this is a common symptom of lymphosarcoma], the pros and cons of splenectomy should be discussed with your veterinarian.

The most common eyelid neoplasm of dogs is a Meibomian adenoma.4 This neoplasm arises from the Meibomian gland but is observed at the eyelid margin, near the Meibomian orifice (Figure 5).

The most common sites of tumor development include the head, pinna, and neck, especially in young dogs.3 More rarely, neoplasms may occur on the trunk and extremities, and frequently involve the feet and toes of older individuals (KSL, personal observation).