Purpose of Study: Dry eye (keratoconjunctivitis sicca) is
a common ocular disease in dogs that leads to discomfort and vision loss.
Not exact matches
«Future research should focus on identifying
common genes, immune responses and environmental exposures that may link these two
diseases,» says first author Lauren Dalvin, M.D., a Mayo Foundation Scholar in
Ocular Oncology.
Potential projects include identifying
common pathways that modify retinal degenerative
disease from a large collection of actively maintained mouse models; determining molecular networks implicated in pathological disruption of the retinal pigment epithelium; identifying molecular pathways that regulate postnatal
ocular growth; and using mouse models to assess the pathogenic role of gene variants that increase the risk of age - related macular degeneration as identified by human genome - wide association studies.
Besides the dog's general state of health, the most
common symptoms of this
disease are manifested on a neuromuscular, dermatological, cardiovascular, reproductive and
ocular level.
A detailed eye examination is also essential since
ocular disease is
common in hypertensive cats.
Feline Herpesvirus type 1 (FHV - 1) is believed to be the most
common cause of
ocular disease in cats.
Ocular disease is a
common sequel to «visceral larval migrans».
Below are some of the
common specialty areas that we have experience with: - Infectious
diseases: Tick - borne
disease (Lyme
disease, Ehrlichiosis, Rocky Mountain Spotted Fever, Bartonella), systemic and local bacterial infections, feline and canine viral
disease - Hematology: Immune - mediated hemolytic anemia, thrombocytopenia, leukemia, bone marrow
diseases - Oncology: Surgical and chemotherapy management, lymphoma, mast cell tumors, hemangiosarcoma, osteosarcoma, fibrosarcoma, mammary neoplasia, as well as benign and malignant skin masses such as adenomas and cysts - Urology: Kidney failure, bladder infections, stones / crystals, prostatic
disease, pyelonephritis, FLUTD, protein - losing nephropathy, glomerulonephritis - Endocrine: Hormonal
diseases such as hyper - and hypothyroidism, diabetes mellitus, cushings
disease, addison's
disease, endocrine skin
disease - Gastroenterology: Chronic vomiting and / or diarrhea, inflammatory bowel
disease (IBD), stomach ulcers / gastritis, colitis, pancreatic disorders, liver
disease, protein - losing enteropathy - Respiratory
disease: Feline asthma, canine chronic bronchitis, upper respiratory viral
disease, pleural effusion, laryngeal paralysis - Cardiology: Heart murmurs and arrhythmias, heart failure, heartworm
disease, hypertension - Ophthalmology: Gaucoma, cataracts, uveitis, corneal
disease,
ocular surgery - Allergic
disease: Allergic dermatitis, food allergies, flea allergy, and allergic gastrointestinal and respiratory
disease
The information derived from these exams will help the individual breeder and the breed club to avoid heritable
ocular diseases with potential for blindness from becoming
common in this breed.
It is difficult to make broad interpretations about
ocular diseases common to Irish Wolfhounds using this relatively small sample of the population; however, cataracts, corneal dystrophy, and distichiasis were the most commonly identified problems in this clinic.
While acute liver & kidney
disease are still
common, other
common problems include: thrombocytopenia & coagulopathy; fever & nonspecific signs such as anorexia, vomiting, lethargy; muscle pain; (peri)
ocular inflammation; & chronic hepatic & / or renal
disease.
Congenital glaucoma is rare in the dog [133] and secondary glaucoma, which is the most
common form of the condition observed in the dog, arises as result of antecedent or concurrent
ocular disease, so is not itself inherited, although the primary, causal condition might be.
These will help rule out
common diseases that senior pets are prone to (such as dental
disease, underlying metabolic
diseases like kidney and liver
disease, endocrine
diseases such as diabetes or thyroid, heart
disease, arthritis,
ocular diseases, dementia, and even cancer are all more
common in senior dogs and cats, and can be detected early by your veterinarian.