Sentences with phrase «common on all variants»

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The researchers computed a genetic risk score for each participant based on 76 common variants known to be associated with elevated risk of obesity, and analyzed this score in the context of accelerometer data and participants» BMIs.

The most notable of these common genetic variant is HMGA2, which exerts about a 0.3 cm effect on height.

«There are no common variants with large effects,» says Lavinia Paternoster, a geneticist at the University of Bristol in the United Kingdom, who plans to work with Kayser in the future on finding more facial genes.

Furthermore, the cohanim were much more likely to carry a specific variant of another length of DNA found elsewhere on the Y chromosome than their lay counterparts, suggesting that they share a common ancestor who had this genetic signature.

They include rare variants that have a strong impact on risk and common variants that are low risk.

They found a genetic variant on chromosome 9 that was much more common in people who had suffered a heart attack.

It will build on the recently completed HapMap, which describes how blocks of DNA tagged by common variants, called single - nucleotide polymorphisms (SNPs), vary in different populations (ScienceNOW, 26 October 2005).

Other medical sequencing projects will use DNA sequencing to: discover new genes that are involved in common diseases; identify the genes responsible for dozens of relatively rare, single - gene (autosomal Mendelian) diseases; sequence all of the genes on the X chromosome from affected individuals to identify those involved in sex - linked diseases; and survey the range of variants in genes known to contribute to certain common diseases.

deCODE is delivering on the promise of the new genetics.SM Visit us on the web at www.decode.com; on our diagnostics site at www.decodediagnostics.com; for our pioneering personal genome analysis service, integrating the genetic variants included in these tests and those linked to another twenty common diseases, at www.decodeme.com; and on our blog at www.decodeyou.com.

The alliance will employ Illumina's platform for high - multiplex single - nucleotide polymorphism (SNP) genotyping to develop tests for gene variants deCODE has previously shown to have impact on the risk of a growing number of common diseases with major public health impact.

Reykjavik, ICELAND, December 16, 2009 — Scientists at deCODE genetics, Inc. (Nasdaq: DCGN) publish in the journal Nature the discovery of a version of a common single - letter variant in the sequence of the human genome (SNP) with a major impact on susceptibility to type 2 diabetes (T2D).

The most common approach is to focus on protein - truncating variants or PTVs (sometimes also called loss - of - function variants *) that terminate or substantially alter the protein sequence.

At the same time, we are working to identify the common thread of variants we and others have discovered on chromosome 8q24 that confer risk of several forms of cancer, including prostate, breast, colorectal and now bladder.

Prior to joining CRI, Vanessa was a postdoctoral fellow at NYU School of Medicine, studying the role of a common gene variant and its effects on Graft - Versus - Host - Disease.

A Common variant on chromosome 9p21 affects the risk of myocardial infarction.

Common sequence variants on 20q11.22 confer melanoma susceptibility.

deCODE is delivering on the promise of the new genetics.SM Visit us on the web at www.decode.com; on our diagnostics site at www.decodediagnostics.com; for our pioneering personal genome analysis service and new Cardio and Cancer scans, integrating the genetic variants included in these tests and those linked to another twenty common diseases, at www.decodeme.com; and on our blog at www.decodeyou.com.

They've also done a great deal to shed light on the genetic architecture of this common complex disease, particularly as far as coding variants are concerned.

deCODE is delivering on the promise of the new genetics.SM Visit us on the web at www.decode.com; on our diagnostics site at www.decodediagnostics.com; for our pioneering personal genome analysis service and new focused disease scans, integrating the genetic variants included in these tests and those linked to another twenty common diseases, as well as for our new deCODEme Cardio ™ and deCODEme Cancer ™ scans, at www.decodeme.com; and on our blog at www.decodeyou.com.

Back in 2010, Goldstein and colleagues proposed the concept of «synthetic association» — the idea that common GWAS signals may be due to individually rare causal variants which cluster on certain common haplotypes.

Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits.

These types of studies usually contain small sample sizes and focus on identifying large, rare variants in the genome rather than smaller, more common variants that may also drive disease pathology.

Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor - positive breast cancer.

A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction.

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.

Variants of Unknown Significance (VUS) on clinical reports are increasingly common, particularly as panels expand.

Common variants on chromosone 5p12 confer susceptibility to estrogen receptor - positive breast cancer.

The paper, «Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer,» can be found at www.nature.com/ng.

Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.

Initiated in February 1998, and covering up to 12 common diseases, the five - year collaboration is focusing on the discovery of gene variants that predispose and / or contribute to the development of these diseases, with a major emphasis on six of them.

Based on the proportions of SNP variants in the human population as estimated from a population - level mitochondrial database (mtDB)[50], the probability of sharing all 6 SNPs in common between VP42 and LNCaP by random chance alone is estimated at less than 0.00146 %.

deCODE discovered the first variant, a SNP called rs 401681, in its gene discovery work on basal cell carcinoma (BCC), a common form of skin cancer.

Researchers analyzed samples from more than 4,000 Huntington's patients and found that variants on two specific chromosomes were more common in patients that showed movement disorders at atypical times.

Genome - wide association study of migraine implicates a common susceptibility variant on 8q22.1.

It is very likely that you have a genetic variant on a gene known as the MTHFR gene which is responsible in part for a very common and necessary chemical reaction known as methylation.

This is my most common variant on the long over lean theme: Just add jacket.

The attached photo shows common wheels on the Toyota B2500 and variants.

LMR is a common term in the seduction community, and is just a variant on the term «cold feet».

All the ZenFone 3 models unveiled thus far share some common characteristics, such as metal bodies, a fingerprint sensor, variants don a full metal design makeover, and fingerprint support embedded on the back of the phones.

Purpose: We were investigating the role of a common canine genetic variant on the condition of pulmonary hypertension.

In this video, Roger shares his thoughts on the Star Wars Luke Skywalker Eachez Vinylmation, on the common and the variant version.

The Greek works of the 1970s, in particular, many of which represent a more politically and socially pointed variant on an idiom of found - object assemblage similar in sensibility to Italian Arte Povera, share an aesthetic as well as a range of references common to much of the more recent work seen throughout the Documenta proper — though expressed in a far more rigorous and authentic manner.

They found that variants of PCA applied to NOAMER tree - ring network had minimal impact on the final reconstruction, as long as the common climatological information in the proxy set was retained.

The most common variant is, «Well, you can't operate on yourself, can you?

According to some experts, «few applicants would move into or out of standard risk pools because genomic information about currently known common variants seldom substantially affects mortality risk estimation already based on phenotype and family history,» and «there is at present insufficient benefit to warrant the addition of predictive genomic data to actuarial risk stratification models.»

Best Life Insurance Policy While there are many different variants of life insurance policies out there, we will keep our focus on some of the most common and important policy types.

While there are many different variants of life insurance policies out there, we will keep our focus on some of the most common and important policy types.

Researchers have compiled a list of the most common malware variants which may be active on networks today.