«Most previous studies aggregate
all comorbidities into an index with little consideration of how a specific comorbid condition can impact lung cancer outcomes in an individual,» Islam said.
Not exact matches
«For the anesthesiologist, a number of factors come
into play, including patient
comorbidities and preferences as well as other practice specific factors, such as the choice for anticoagulation, but regional anesthesia should, at the very least, be considered in every patient.»
They also categorized the men
into subgroups based on extent of prior
comorbidity, including prior heart attack.
Over her career, Professor Goldstein, a Fellow of the British Psychological Society, has undertaken internationally recognised research
into the neuropsychological and broader psychological consequences of neurological disorders and their
comorbidities, with particular reference to motor neurone disease.
Support for
comorbidities will be particularly important as students move
into adolescence.
For our fifth and final addition in OnlineCounselingPrograms.com's blog series «Mental Health and...», we look
into comorbidity between mental illness and substance use disorders, specifically how the two can be influential of one another and may typically occur at the same time.
Childhood ADHD may be a risk factor for later criminal behavior.5, 23 — 26 Previous research also suggests that ADHD may be associated with increased mortality, particularly from suicide or accidents.23 We have previously described risk factors for ADHD, childhood
comorbidities, treatment history, and educational outcomes through age 19 years for this cohort of ADHD cases.27 — 32 However, no study to date has reported mortality rates in a population - based cohort of childhood ADHD cases followed
into adulthood.
Attention - deficit / hyperactivity disorder (ADHD) is the most common childhood neurodevelopmental disorder.1, 2 Important questions about adult outcomes for childhood ADHD remain, including the rate of persistence of ADHD
into adulthood, the psychiatric
comorbidities of adult ADHD, and the risk of serious adverse outcomes, such as criminality and mortality.
It is therefore particularly concerning that we found high rates of psychiatric
comorbidity among our population - based sample of adult subjects with a history of childhood ADHD, regardless of whether ADHD persisted
into adulthood (80.9 % and 47.0 %
comorbidity rates, respectively).
Barkley et al found increased rates of comorbid substance abuse disorder, anxiety disorder, mood disorder, personality disorders, and disruptive behavior disorders among adults with ADHD that had persisted from childhood
into adulthood.23 Adults whose childhood ADHD did not persist also had increased rates of psychiatric
comorbidity, although lower than those with persistent ADHD (47.3 % vs 84.3 %).23 Other smaller studies also report elevated rates of psychiatric
comorbidity (65 — 89 %) among adults with ADHD.15 — 22 However, these studies used nonrepresentative samples of children referred to specialty treatment programs for ADHD.
Both types of disorder were entered together
into the models to control for
comorbidity.31
The adolescent and young adult with ADHD is at risk for school failure, emotional difficulties, poor peer relationships, and trouble with the law.29, 30 Factors identifiable in younger youth that predict the persistence of ADHD
into adulthood include familiality with ADHD and psychiatric
comorbidity — particularly aggression or delinquency problems.28,, 29,31,32
Fortunately, conducting randomized trials over the decades, intervention researchers have produced numerous manual - guided, evidence - based treatments (EBTs) for depression, anxiety, and conduct in youth.2 Unfortunately, these treatments have not been incorporated
into most everyday clinical practice.3 - 5 A common view is that the complexity and
comorbidity of many clinically referred youths, whose problems and treatment needs can shift during treatment, may pose problems for EBT protocols, which are typically designed for single or homogeneous clusters of disorders, developed and tested with recruited youths who differ from patients seen in everyday clinical practice, and involve a predetermined sequence of prescribed session contents, limiting their flexibility.3 - 8 Indeed, trials testing these protocols against usual care for young patients in clinical practice have produced mixed findings, with EBTs often failing to outperform usual care.7, 9
We did find an effect of non-anxiety comorbid disorders on externalizing symptoms; non-anxiety
comorbidity did have a negative impact on change in externalizing symptoms in anxious children when suppressor effects were taken
into account.
Using baseline diagnoses, preschoolers were categorized
into 1 of 3 hierarchical diagnostic groups: (1) the MDD group was composed of those who met criteria for MDD and had any other
comorbidity (n = 75), (2) the psychiatric group was composed of those who met criteria for any anxiety and / or disruptive disorders but did not have MDD (n = 79)(anxiety disorders included separation anxiety disorder, generalized anxiety disorder, and posttraumatic stress disorder.
Yet, disorders tend to co-occur, and when
comorbidity is not taken
into account, pairwise associations may simply represent indirect effects rather than direct associations.36, 37 For example, bivariate analyses may suggest that childhood anxiety disorders predict adolescent depression, but this association could be accounted for by
comorbidity between childhood anxiety and depression.