As computational biologists, they employ
comparative genomic approaches to understand the evolution and function of protein families and their ultimate role in human disease.
Branscomb also sees lots of opportunities in «techniques that are transforming scientific methodology, such as array technology,
comparative genomic approaches, proteomics, sequence analysis.»
2012 In this thesis, I investigate the genetics of neuropsychiatric disorders by analysing large data sets derived from high - throughput experiments, using novel
comparative genomics approaches.
«Our goal is to use
comparative genomics approaches to fill in gaps in our understanding of how plant reproduction works and to define the aspects of the mechanisms we've discovered so far that are either ancient or new innovations.»
Not exact matches
The Parasite
Genomics group uses
comparative and functional
genomics approaches to investigate the biology of helminths and protozoan parasites.
To achieve these goals, his group uses a variety of organisms and experimental
approaches, including mouse transgenesis, ES and TS cell culture, chick embryology, and
comparative genomics.
The lab's goal is to develop computational
approaches to study phenotype - genotype associations using the power of
comparative and evolutionary
genomics, followed by experimental verifications.
We are investigating these and other allied questions using evolutionary
genomic approaches, by performing
comparative analyses of plant genomes, transcriptomes and proteomes.
Here, we discuss and illustrate the strengths and weaknesses of
approaches for the annotation and classification of important elements of protein - coding genes, other
genomic elements such as pseudogenes and the non-coding genome,
comparative -
genomic approaches for inferring gene function, and new technologies for aiding genome annotation, as a practical guide for clinicians when considering pathogenic sequence variation.
To study such effects, the
Comparative Genomics group employs computational and evolutionary
approaches to analyze whole genome datasets for predicting
genomic, epigenetic and expression differences between individuals.
Paul's research expertise includes: cultivation of marine bacteria, microbial distribution and interactions with marine plants and invertebrates, sequence - based
approaches to the discovery of natural products from marine microbes,
comparative genomics, microbial chemical ecology, molecular evolution and natural product biosynthesis.