The study divided data into two segments to
compare outcomes of patients treated before and after 2002, when the Pediatric End - Stage Liver Disease system (PELD) was instituted.
«Our study is one of the first to directly
compare outcomes of patients treated at the same hospital during a set period of time.
Not exact matches
Under PPACA, certain fees, known as
Patient - Centered
Outcomes Research Institute («PCORI») fees, have been established for funding medical research and comparing outcomes of various medical tec
Outcomes Research Institute («PCORI») fees, have been established for funding medical research and
comparing outcomes of various medical tec
outcomes of various medical techniques.
How do APRN (advance practice registered nurses)
patient outcomes compare with
outcomes of other providers?
For the purposes
of this economic evaluation, the forms were initially used in a related study funded by the National Institute
of Health Research (NIHR) research for
patient benefit programme «assessing the impact
of a new birth centre on choice and
outcome of maternity care in an inner city area,» which will be reported in full elsewhere,
comparing the costs
of care in a free standing midwifery unit with care in an obstetric unit in the same trust.16 The data collected included details
of staffing levels, treatments, surgeries, diagnostic imaging tests, scans, drugs, and other resource inputs associated with each stage
of the pathway through intrapartum and after birth care.
We
compared outcomes after medical versus surgical management
of biliary tract disease in pregnant
patients.We reviewed the clinical course
of patients with symptomatic cholelithiasis during pregnancy from 1992 to 2002 at two university hospitals.Seventy - six women with 78 pregnancies were admitted with biliary tract disease.
Data
comparing the rates
of VBAC, as well as maternal and neonatal
outcomes, after TOLAC to those after planned repeat cesarean delivery can help guide obstetricians or other obstetric care providers and
patients when deciding how to approach delivery in women with a prior cesarean delivery.
While the researchers did not directly
compare survival rates and neurological
outcomes with whether individual
patients received bystander CPR or defibrillation, they did find increases in both over the duration
of the study.
To date, no systematic review has
compared the direct and indirect effects
of these three different training modalities on the
outcomes of blood sugar control and blood fats in
patients with type 2 diabetes.
The field is also expanding into
patient - centered
outcomes research, so not just
comparing drug A with a placebo, but drug A versus drug B.» In spite
of the uncertainties, she says, «It's an exciting time because we have a lot to learn.»
In the new study,
patients receiving angioplasty with the new stents had a 47 percent higher risk
of one
of the
outcomes identified as a primary endpoint in the study: death, heart attack and subsequent procedure to clear blocked arteries, as
compared to
patients who received bypass.
«Although radiosurgery has been shown to be an effective post-surgical treatment for metastatic brain tumors, previous studies did not
compare patient outcomes from a single hospital over the same period
of time,» said N. Scott Litofsky, M.D., chief
of the Division
of Neurological Surgery at the MU School
of Medicine and senior author
of the study.
The researchers then
compared the images with the
patients»
outcomes after five months
of chemotherapy.
The researchers assigned risk categories to each
of the operations performed in the data pool, including colorectal and liver resections, and then
compared 30 - day postsurgical
outcomes among
patients within similar risk groups.
«The use
of a ceramide - infused barrier significantly decreased cost and increased satisfaction with
patient - reported
outcomes compared to conventional skin barriers,» said Janice C. Colwell, MS, RN, CWOCN, FAAN,
of University
of Chicago Medicine, a principal author
of the study report.
In devising their experiment, the researchers took advantage
of ambulance company practices that essentially provided a randomized group
of patients to study, making it possible to
compare outcomes at different hospitals.
The study, Developing an Interventional Stroke Service: Improving Clinical
Outcomes and Reducing Cost and Delivering Great Cost Savings Benefits to Health Economy, conducted at the University Hospital
of North Midlands, Stoke - on - Trent, U.K., found that mechanical thrombectomy (the use
of a device to retrieve a clot from the vessel) in the treatment
of stroke reduced the average stroke
patient's hospital stay to 14 days when
compared to previously recorded 90 days.
The results also indicate that older
patients in any age group had higher incidence
of all
outcomes (nonfatal complications and death) if they had diabetes for a longer,
compared with shorter, duration
of time.
«By reducing bleeding with comparable rates
of MACCE and stent thrombosis, bivalirudin significantly improved overall 30 - day and one year
outcomes,
compared with both heparin alone and heparin plus tirofiban in
patients with AMI undergoing primary PCI,» said Gregg W. Stone, MD, the study's senior author.
Averaged over a four - year follow - up period, operatively treated
patients at least 80 years
of age, had significantly greater improvement in all primary and secondary
outcome measures
compared with
patients at least 80 years
of age who received nonsurgical treatment.
Comparing Options for Management:
Patient - Centered
Outcomes for Uterine Fibroids (
COMPARE - UF) is a voluntary registry
of 10,000 women with uterine fibroids funded by the
Patient - Centered
Outcomes Research Institute (PCORI) and the Agency for Healthcare Research and Quality (AHRQ).
The researchers next will turn to analyzing the presence
of myoferlin in samples from numerous human tumor types available in an Ohio State tissue bank, which will allow them to
compare protein levels in tumors to clinical
outcomes for the
patients who provided the samples.
In the study, researchers from Kansas City VA Medical Centre in Kansas City, USA, examined the effect
of TRT on cardiovascular
outcomes by
comparing incidents
of heart attack, stroke, and all - cause mortality among different sub-populations
of treated and untreated
patients.
The current study analysed
outcomes in the subgroup
of patients with EGFR expressing tumours
compared to those with no EGFRs.
The odds
of a good stroke
outcome were 75 % greater for
patients given alteplase within 3 hours
of initial stroke symptoms,
compared with those who did not receive the drug; for those given the drug between 3 and 4 · 5 hours post-stroke there was a 26 % increased chance
of a good
outcome; while for those with a delay
of more than 4 · 5 hours in receiving treatment, there was just a 15 %, not statistically significant, increase in the chance
of a good recovery.
A phase 2 trial showed a reduction in the combined
outcome of death or myocardial infarction (heart attack) in
patients treated with otamixaban
compared with unfractionated heparin (UFH) plus eptifibatide (an antiplatelet drug) and showed similar bleeding rates with otamixaban at midrange doses.
This data was then
compared with
patients»
outcomes, including heart attack or the occurrence
of major adverse cardiac events within 30 days.
The results
of the Endovascular Therapy Following Imaging Evaluation for the Ischemic Stroke (DEFUSE 3) trial, presented at the International Stroke Conference 2018 in Los Angeles and published on Jan. 24 in the New England Journal
of Medicine, demonstrated that physically removing brain clots up to 16 hours after symptom onset in selected
patients led to improved
outcomes compared to standard medical therapy.
«The first task is to
compare the medical
outcomes of patients when alarms sound within their area vs. when alarms are intentionally muted and sent to staff via pagers or cell phones,» she said.
Looking at the components
of the primary
outcome separately, only hospitalizations, specifically for heart failure, had a significantly lower incidence for those taking spironolactone
compared to placebo, with 206
patients (12.0 percent) in the spironolactone group undergoing hospitalization versus 245
patients (14.2 percent) in the placebo group.
The researchers
compared hemoglobin levels
of these
patients and their
outcomes within one year
of surgery.
Christiani would like to see an experiment that
compares the survival
of patients administered large doses
of the vitamin during treatment and follow - up periods against the
outcomes of people who rely on diet and conventional therapy alone.
Michelle Hladunewich, MD (Sunnybrook Health Sciences Centre, in Toronto) and her colleagues assessed the effects
of such intensive dialysis on pregnancy
outcomes by
comparing patients from Toronto with that from the United States.
Patients who underwent open - heart surgery in the afternoon experienced better health outcomes compared to those who got operated on in the morning, study authors found after six years of observing nearly 600 patients who underwent heart valve repl
Patients who underwent open - heart surgery in the afternoon experienced better health
outcomes compared to those who got operated on in the morning, study authors found after six years
of observing nearly 600
patients who underwent heart valve repl
patients who underwent heart valve replacement.
Favourable
outcomes, ranging from moderate disability to good recovery, occurred in only a quarter
of the
patients in the hypothermia group
compared with more than a third
of patients in the control group.
PD - L1 expression intensity was scored on a scale
of 0 to 3 — with» 0» signifying no expression,» 1» signifying weak expression,» 2» moderate, and» 3» strong — and then
compared the score with survival data and
outcomes from those
patients.
«This study allowed us to look more closely at the long - term
outcomes of patients in whom the localized cancer in the prostate was successfully eradicated and
compare them to
patients whose disease persisted within the prostate following treatment,» adds Dr. Krauss.
As to the reason why certain racial and ethnic minorities have poorer rates
of treatment for cardiovascular disease and generally have poorer cardiovascular health
outcomes compared to white
patients, Dr. Ladapo concludes that no one has really explored whether there could be disparities in cardiac stress testing, which is a mainstay
of diagnosing
patients with heart disease in this country.
Both one and two year rates
of adverse
outcomes compared favorably with historical performance criteria established among medically managed
patients with aortic stenosis.
«Exploratory analyses
of several secondary
outcomes indicated that the sedation protocol was associated with a difference in
patients» sedation experience;
patients in the intervention group were able to be safely managed in a more awake and calm state while intubated, receiving fewer days
of opioid exposure and fewer sedative classes without an increase in inadequate pain or sedation management or clinically significant iatrogenic [consequence
of treatment] withdrawal
compared with
patients receiving usual care, but they experienced more days with reported pain and agitation, suggesting a complex relationship among wakefulness, pain, and agitation,» the authors write.
Sixty - three percent
of patients who did not receive epinephrine achieved this
outcome,
compared to only 19 percent
of those who received epinephrine.
«Triple - negative breast cancers tend to be more aggressive
compared to other types
of breast cancers, and being able to predict response to therapy could greatly impact treatment decisions and
patient outcomes,» says study author Shaveta Vinayak, MD, oncologist at UH Case Medical Center and Assistant Professor at Case Western Reserve University School
of Medicine.
Using data from two academic institutions, Derosa and colleagues
compared outcomes in
patients with advanced RCC or NSCLC who had received antibiotics within 30 days
of beginning immunotherapy against
outcomes in those who did not.
[79] A total
of 86
patients with advanced mucosal melanoma were included in the nivolumab monotherapy analysis, and 35
patients with mucosal melanoma were included in the combination therapy analysis; in addition,
outcomes in these
patients were
compared with
outcomes in
patients with cutaneous melanoma who were treated in these clinical studies.
Non-controlled, observational study
comparing outcomes of non-study
patients to those participating in a controlled clinical trial.
The prognosis
of each group
of patients was examined by Kaplan - Meier survival estimators, and the survival
outcomes of the two groups were
compared by log - rank tests.
The researchers
compared patient outcomes in surgeries which did not experience a handover
of anesthesia care with those where the primary anesthesiologist transferred care to a colleague and did not return to the operating room.
The inpatient setting,
compared with the outpatient setting, offers a unique advantage when studying
patient outcomes between male and female physicians: within a given hospital, there is plausibly less selection
of the physician by the
patient or
of the
patient by the physician.
In a substudy, review
outcomes were also
compared across different types
of clinical research, based in large part on the designations and definitions derived from a number
of sources, including a report by Nathan, 14 the Institute
of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association
of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1
of the following: (1)
patient - oriented studies
of mechanisms
of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3)
patient - oriented research focusing on development
of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies
of normal human behavior); (6) health services research; and (7) use
of deidentified human tissue.
The use
of anti-CD19 chimeric antigen receptor T cells induced a nearly sixfold higher rate
of complete response
compared with historical
outcomes in
patients with refractory, aggressive non-Hodgkin lymphoma.