Sentences with phrase «compare tested animals»

Not exact matches

Proposals to compare human - based tests with animal - based approaches have been strongly supported by members of the UK parliament.

Hughes's winning research proposed using microarray techniques to compare the genomes of a variety of vertebrate animals to test for common regulatory elements that determine gene expression.

The goal is to compare these engineered livers with animal models, with an eye toward replacing animal testing

Experiments with mice show that after just four weeks on a high - fat or a high - sugar diet, the performance of mice on various tests of mental and physical function began to drop, compared to animals on a normal diet.

In this research, after just four weeks on a high - fat or a high - sugar diet, the performance of mice on various tests of mental and physical function began to drop, compared to animals on a normal diet.

Compared to 1990, the number of tests involving animals bred with harmful genetic defects rose by 28 000, to 170 000, and transgenic creatures were subjected to 62 000 procedures, 14 000 more than in 1990.

«Compared to mice, our large animal stroke model is a more rigorous test of potential therapeutics with findings that are likely more clinically relevant,» said Franklin West, an associate professor in the College of Agricultural and Environmental Sciences and senior author of the paper describing the model.

They compared the animals» ability to negotiate a radial - arm water maze, a standard test of cognitive ability, with that of regular J20 mice and of normal mice at 4, 9, and 14 months of age.

(Right) Autologous tier 2 serum NAb titers (IC50) in 50 animals immunized with various uncleaved gp140 proteins, compared to titers in the 30 rabbits given the BG505 or B41 SOSIP.664 trimers described here (see legend of Fig. 2 in the full article for details; P < 0.0001, two - tailed Mann - Whitney test).

It is also necessary to compare the doses humans have in their bodies with the doses test animals have in their bodies.

The values show mild statistically significant difference in number of progeny laid by mutant worms CK123 compared to wild type N2 animals during the day 3 (Two Tailed T Test, p = 0.04962).

Our findings first confirmed previous work with this model in demonstrating that compared to undefeated control animals, mice most susceptible to social defeat stress demonstrated a number of abnormalities in social avoidance, depression and anxiety as measured by routine test procedures.

It is the first time that both models were compared using proprietary, very sensitive behavioral tests that may have the capability to increase even predictive drug testing in animals models of AD.

As a general rule, work with cancer cell lines is an easy and cheap way to investigate biological concepts, test drugs and validate methods, mainly because cell lines are cheap compared to animal research, readily available, easy to grow, and there are few concerns around ethics and informed consent.

In an animal study, Alzheimer's mice that ate an almond rich diet performed much better on memory tests compared to mice that ate a standard diet.

In animal testings, a 33 % belly fat gain was seen in animals on a high trans fat diet compared to the ones on a diet high in monounsaturated fats (32).

In animal cases, she said, standard DNA testing may cost about $ 300, compared with several thousand dollars for human tests.

«The results of laboratory tests on a patient are compared to reference ranges established by measuring the laboratory parameters in a group of normal animals.

Tests on organic produce, both vegetable and animal - derived, have shown consistently higher levels of vitamins, trace minerals and other essential nutrients compared to conventionally grown crops.

In line with our caring science approach and the 3Rs guidelines for animal research (reduction, replacement, refinement), the sensitivity of the QLF technique means that fewer animals are required for testing the efficacy of oral hygiene products compared to traditional plaque measurement techniques.

To establish whether a kennel has parvovirus, test some of the breeding animals for antibodies, their titres will be much higher if they have been naturally exposed compared to post-vaccinal levels (such tests can be carried out by Companion Animal Diagnostics, University of Glasgow Veterinary School).