Seeking a better understanding of the hormone, University of Washington endocrinologist David Cummings
compared ghrelin levels in people who had lost considerable amounts of weight through diet with those who shed pounds by means of gastric bypass surgery — a technique that reduces the capacity of the stomach and seems to damage its ghrelin - producing capacity as well.
Not exact matches
In one study, after just two consecutive nights of four - hours» sleep, test subjects had a 28 percent higher
ghrelin (hunger) hormone
level and 18 percent lower leptin (satiety) hormone
level in their blood
compared with subjects who had spent 10 hours a night in bed.
To be more sure of these results, the study also
compared the effects of carbonated drinks in 20 young men, which resulted in finding that they, too, had higher
ghrelin levels after drinking the carbonated drinks versus drinking flat soda or still water.
Similar fructose increases have been reported in healthy volunteers who consumed fructose loads between 0.5 and 0.75 g / kg34 and in individuals who consumed fructose - sweetened beverages with mixed meals.35 Leptin and
ghrelin levels were indistinguishable following acute ingestion of glucose or fructose, a finding possibly attributable to the short time interval of observation; leptin
levels typically change 4 to 6 hours after glucose administration.36 Although fructose was previously reported to be less effective than glucose in suppressing
ghrelin, such differences may be attributable to the different conditions and timing of
ghrelin measurements.10 Little is known about the acute PYY response to fructose ingestion
compared with glucose ingestion, although 1 study in rats found higher rather than lower PYY
levels after 24 hours of glucose but not fructose feeding.11 Whether such disparities are related to study design or species differences remains uncertain.