«What there generally hasn't been in the literature are very many studies
comparing autism and schizophrenia directly,» Foss - Feig says.
Perhaps the most valuable takeaway from
comparing autism and schizophrenia's social features would be better treatment.
Not exact matches
To grasp the implications, Stefánsson's team
compared the whole - genome sequences of 78 Icelandic people diagnosed with
autism or
schizophrenia with the sequences of their fathers
and mothers.
Statistically significant hazard ratios for specific groups of psychiatric disorders were found for
schizophrenia and psychoses (1.27, 1.16 - 1.38), affective disorders (1.32, 1.25 - 1.39), anxiety
and other neurotic disorders (1.37, 1.32 - 1.42), mental
and behavioural syndromes including eating disorders (1.13, 1.04 - 1.24), mental retardation (1.28, 1.17 - 1.40), mental development disorders including
autism spectrum disorders (1.22, 1.16 - 1.28),
and behavioural
and emotional disorders including attention deficit hyperactivity disorder (ADHD)(1.40, 1.34 - 1.46), when
compared with rates in naturally conceived children.
First, an analysis of genomic data from 6,000 patients with
autism spectrum disorders, 1,000 patients with bipolar disorder,
and 2,500 patients with
schizophrenia by co-first author Pierre - Marie Martin, PhD, a postdoctoral researcher in Cheyette's lab, revealed that disruptive mutations in the main neuronal form of DIXDC1 were present about 80 percent more often in psychiatric patients (0.9 percent had mutations)
compared to healthy controls (0.5 percent had mutations).