Research on secondhand smoke conducted by researchers with industry ties is 88 times more likely to find no harm; industry - funded studies
comparing cholesterol drugs are 20 times more likely to favor the sponsor's drug.
Not exact matches
It was also the first
drug to prove that lowering
cholesterol could prevent recurrent heart attacks
compared to a placebo in a randomized clinical outcomes trial.
In March 2008, a 15,000 - person study
comparing Crestor (rosuvastatin) against placebo in two groups of outwardly healthy people with low levels of LDL
cholesterol and high levels of CRP was stopped early — a «stunning» outcome, the lead researcher said at the time — because the reduction in cardiac events was so marked among the participants taking the
drug that to continue the trial and deprive the placebo group of the
drugs benefits would have been unethical.
In fact, when the
cholesterol - lowering ability of steamed Brussels sprouts was
compared with the
cholesterol - lowering ability of the prescription
drug cholestyramine (a medication that is taken for the purpose of lowering
cholesterol), Brussels sprouts bound 27 % as many bile acids (on a total dietary fiber basis).
The ability of pear fibers (and other fruit fibers) to bind bile acids has actually been
compared to the
cholesterol - lowering
drug cholestyramine, with pears showing about 5 % of the ability of the
drug to accomplish this result.
Their statistical analysis of the results implied a 24 % reduction in the rate of coronary heart disease in the group taking the
drug compared with the placebo group; however, nonheart disease deaths in the
drug group increased — deaths from cancer, stroke, violence and suicide.7 Even the conclusion that lowering
cholesterol reduces heart disease is suspect.
One study that
compared the
drug Lipitor and fish oil found that fish oil was more effective than the statin
drug Lipitor in positively affecting the good
cholesterol (HDL),
cholesterol in obese and insulin - hesitant men.
Research published in November 2009 showed that patients taking the
cholesterol drug Zetia were more likely to suffer serious and possibly life - threatening side effects
compared with patients who were prescribed another
drug to lower
cholesterol.