Sentences with phrase «comparing gene expression changes»

It is interesting to note that when comparing these gene expression changes between ER - α - positive and negative lines, very little correlation was seen between the cell types, which is supportive of previously published data (36).

By comparing gene expression changes induced upon expression of wild - type and mutant alleles, we inferred the activity of specific alleles.

Not exact matches

They compared changes in gene expression in 37 of them who developed suicidal feelings with previously published work and with post-mortem samples of 26 men who had killed themselves.

But the researchers found no significant changes in the expression of genes known to be involved in calcification from prior studies comparing strains with dramatically different calcification levels.

When Bordenstein and Brucker compared gene expression patterns in normal and microbe - free offspring, they found significant changes in many of the genes involved in the immune response (Science, doi.org/m87).

This same feature, tumor heterogeneity, may reduce the ability to identify critical gene expression changes when comparing mean gene expression in adjacent tumor and normal tissues, as tumors of the same type may have different sets of genes differentially expressed.

To detect novel changes in gene expression, we used a focused microarray platform to evaluate the expression profile of retinas from hypoxic animals compared to that in retinas isolated from control animals exposed to room air.

The greatest changes in gene expression were seen when the V − S − and V+S − fractions were compared (Figure 4B) with over a thousand genes changing in each direction.

These reporters will give us the ability to sort infected cultures to analyze changes in gene expression in directly infected cells and bystander cells and compare to uninfected cells.

Given that changes in gene expression profiles will likely be seen after a short period exposure to drugs, and that most cells had undergone cell death in as little as 8 hours (Fig. 3E — G), we compared gene expression of cells prior to and after 4 hours of exposure to the drugs.

To systematically investigate the effect of P. locustae on the phase change of L. migratoria manilensis, we used a high - throughput sequencing platform (HiSeq 2500; Illumina) to compare gene expression in healthy locusts and locusts infected by P. locustae.