One is to identify disease genes — particularly those involved in conditions with complex origins, such as asthma and heart disease — by
comparing genetic sequences within a group of patients with a given disease.
Comparing these genetic sequences with known data implied that they might be responsible for the synthesis of novel natural products.
By
comparing the genetic sequences of the mutant and normal flies, the researchers found that the forgetful flies had an inactive copy of a gene that he and his Chilean collaborators dubbed Volado (Vol)-- South American slang for absentminded.
The scientists
compared the genetic sequence of five related strains of the species, looking for orphan genes and examining the life cycles of the various genes in the fly genome.
They then
compared genetic sequences with the genome of the still common domestic pigeon (Columba livia) and, based on those comparisons, estimate they captured between 57 and 75 percent of the passenger pigeon's genetics (assuming that its genome was roughly the same size as its relative's).
He compared the genetic sequences in those SIV samples with sequences from the few African green monkey SIV samples he had, as well as to sequences of human HIV - 2 and macaque SIV.
Each year the World Health Organization (WHO),
comparing genetic sequence and antigenic data, makes recommendations about which circulating strains of influenza will make the best matching vaccine.
Using a program that
compared the genetic sequences of each viral strain, the researchers were able to analyze which mutations conferred resistance to each strain of the virus.
The computer
compared the genetic sequence to the database of whale species curated by the Marine Mammal Genetics Group and quickly identified the prey: a pygmy sperm whale.
Not exact matches
For since
genetic identity is partial or somewhat abstract, and the concrete has always a contingent plus
compared to the abstract, of course an enduring individual, i.e., a society or
sequence of occasions, can have contingent or inessential members.
«We used standard DNA
sequencing technology, determined the
genetic types of the samples from traders,
compared them to our wild - caught, known - locality samples and then «ground - truthed» what the traders told us versus what the genetics inferred,» Brown said.
The need to
compare multiple cells» DNA
sequences to distinguish genuine
genetic variants from artifacts limits some of the potential of single - cell
sequencing.
The scientists
sequenced the mitochondrial DNA of 23 Asian bears (including the purported Yetis), and
compared this
genetic data to that of other bears worldwide.
They also
compared the human genomes with recently
sequenced genomes of Neanderthals and Denisovans and found similar
genetic variation, which indicates that the facial variation in modern humans must have originated prior to the split between these different lineages.
They can also
compare E. coli's
genetic makeup with that of some of the other microorganisms
sequenced so far — bakers» yeast, Saccharomyces cerevisiae; Helicobacter pylori, the bacterium responsible for most cases of intestinal ulcers; and Methanococcus thermoautotrophicum, an organism that thrives in hot springs, for example.
After
comparing HA
genetic sequences in five key locations that control the viruses» interactions with infected hosts, the researchers calculated an «antigenic index» for each strain.
To identify
genetic changes likely to be responsible for the giraffe's unique characteristics, including sprints that can reach 37 miles per hour (60 km / h), Cavener and Agaba
compared the gene - coding
sequences of the giraffe and the okapi to more than forty other mammals including the cow, sheep, goat, camel, and human.
Using whole - genome
sequencing, they looked at rare
genetic variants in modern - day British populations and
compared them with variants in the DNA of 10 ancient skeletons.
Investigators
compared DNA from the liquid blood biopsies to DNA tissue samples from the tumor, using mate - pair
sequencing — an inexpensive whole exome
sequencing that can reveal
genetic changes that contribute to tumor growth.
Pavel Pevzner and Glenn Tesler
compared the just -
sequenced mouse genome with its human counterpart and analyzed where rearrangements, a common type of
genetic mutation, occur.
Metabarcoding works by
comparing short
genetic sequence «markers» from unidentified biological specimens to libraries of known reference
sequences.
A research team from Uppsala University has
sequenced the entire genomes of a sample of Cape bees and
compared them with other populations of honeybees to find out the
genetic mechanisms behind their asexual reproduction.
Tohoku University researchers and their international collaborators
compared the genomes of 48 avian species with other vertebrates to identify
genetic sequences specific only to birds.
The authors
compared these ancient DNA
sequences to
genetic data from diverse modern humans, including four Sherpa and two Tibetans from Nepal.
A research team led by Mathew Webster at Uppsala University / SciLifeLab has
sequenced the entire genomes of a sample of Cape bees and
compared them with other populations of honeybees to find out the
genetic mechanisms -LSB-...]
Modern molecular technologies (genomics and other omics), through
comparing nucleic acid and amino acid
sequences across living species, are enabling the identification of
genetic components and patterns stingily conserved by evolution, from those in which times of evolutionary branching of the tree of life can be inferred.
Recent advances in high - throughput deep
sequencing have made it increasingly possible to measure influenza's within - host
genetic diversity and
compare this diversity to the virus's global evolution.
The team used whole genome
sequencing techniques to
compare the
genetic information from the TB bacteria of each patient.
The ClinSeq ® study was
comparing the
genetic characteristics of healthy people and patients with heart disease, and it would involve «full gene
sequencing.»
A research team led by Mathew Webster at Uppsala University / SciLifeLab has
sequenced the entire genomes of a sample of Cape bees and
compared them with other populations of honeybees to find out the
genetic mechanisms behind their asexual reproduction.
In these studies,
sequence data from several thousands of individuals is
compared to find disease - associated genes where cases have a higher load of
genetic variants that are likely to disturb gene function,
compared to the controls.
That data will be
compared with
genetic sequences of thousands of tumors already collected by the National Cancer Institute (NCI), including more than 500 pancreatic cancers.
Chowdhury and his colleagues found that for all six infants, who suffered from a variety of often exceedingly rare
genetic disorders,
sequencing their whole genomes led to a reduction in the length of stay in the NICU by 124 days
compared to control cases and reports from the scientific literature, in which standard array or panel - based
genetic testing may be used.
Findings showed subtle differences between the viral
genetic sequences taken from the vaccinated individuals,
compared to the placebo recipients.