Sentences with phrase «complementary sequences in»

MicroRNAs are short RNA molecules that typically bind to complementary sequences in messenger RNAs, thereby controlling the amounts of specific proteins produced by cells.

Not exact matches

There is no evidence for a benefit to introducing complementary foods in any specific sequence or at any specific rate.

Running their computer algorithm, the biologists found that 5300 genes contained complementary sequences to an miRNA — suggesting that the miRNA could control that gene's expression, they report in the 14 January Cell.

The team integrated three, complementary gene sequencing approaches to look for mutations in tumor cells from SS patients: whole - genome sequencing in six subjects, sequencing of all protein - coding regions (exomes) in 66 subjects, and comparing variation in the number of copies of all genes across the genome in 80 subjects.

Second, they separated the complementary strands of DNA in these fragments before sequencing so they could still use one half of the double helix even if the other half were damaged.

Cloning and sequencing of complementary DNA's from normal and WHHL rabbits, shows that this defect arises from an in - frame deletion of 12 nucleotides that eliminates four amino acids from the cysteine - rich ligand binding domain of the LDL receptor.

Writing for the majority, Judge Alan Lourie concluded that Myriad's basic patents on BRCA1 and BRCA2 sequences were valid because they applied to «isolated DNA,» or complementary DNA (cDNA)-- not DNA as found in the body.

In one experiment, they encoded the same sequence on all the octahedron's tethers, and attached strands with a complementary sequence to gold nanoparticles.

In additional experiments the scientists changed the sequence of some vertices and used complementary strands on different kinds of particles, illustrating that they could direct the assembly and arrangement of the particles in a very precise waIn additional experiments the scientists changed the sequence of some vertices and used complementary strands on different kinds of particles, illustrating that they could direct the assembly and arrangement of the particles in a very precise wain a very precise way.

As they report in two new studies, the pair and their colleagues constructed viral vectors, each one containing an RNA molecule designed to shut down a gene with a complementary sequence.

These customized RNAs include complementary sequences that are tailored to match up with specific DNA sequences in the microbe's genome.

Human transforming growth factor - beta complementary DNA sequence and expression in normal and transformed cells.

With investigations of the conformational properties and interaction stoichiometry of polyribonucleotides of simple and complex sequence (7) and the separation of the complementary strands of DNA and then their renaturation to biologically active duplexes (8), the groundwork was laid for the complementary strand annealing that proved so critical in making gene cloning possible.

The mature miRNA sequence usually starts with A or U, and is often mismatched with the complementary arm, which seems to facilitate arm selection by Argonaute (at least in mammals)(6,9,10).

Most of the downstream genes we looked at experimentally were regulated by miR - 24 recognition of «seedless» complementary sequences.7 We now think that miR - 24 is another example of a «master regulator» of the cell, which acts by directly suppressing the expression of many genes that act in interconnected pathways.

Specifically, we have generated clusters of transcripts that behave the same way under the entire spectrum of the sixty - seven experimental conditions; we have assembled genes in groups according to their time of expression during successive days of ES cell differentiation; we have included expression profiles of specific gene classes such as transcription regulatory factors and Expressed Sequence Tags; transcripts have been arranged in «Expression Waves» and juxtaposed to genes with opposite or complementary expression patterns; we have designed search engines to display the expression profile of any transcript during ES cell differentiation; gene expression data have been organized in animated graphs of KEGG signaling and metabolic pathways; and finally, we have incorporated advanced functional annotations for individual genes or gene clusters of interest and links to microarray and genomic resources.

Two nucleotides complementary to the seed sequence of miR -142-3p were mutated in the pCMV - Neo-APC mutant plasmid.

Ramin Bahrani's talent for orchestrating sequences of tightly wound tension is in full bloom here, as is his complementary knack for quieter grace notes.

«In Tune With The World» Artists include: Some 29 French and international artists presented in two complementary sequences, with works by: Giovanni Anselmo (1934, Italy), Matthew Barney (1967, USA), Christian Boltanski (1944, France), Mark Bradford (1961, USA), James Lee Byars (1932 - 1997, USA), Maurizio Cattelan (1960, Italy), Ian Cheng (1984, USA), Trisha Donnelly (1974, USA), Dan Flavin (1933 - 1996, USA), Cyprien Gaillard (1980, France), Alberto Giacometti (1901 - 1966, Switzerland), Dominique Gonzalez - Foerster (1965, France), Jacqueline Humphries (1960, USA), Pierre Huyghe (1962, France), Yves Klein (1928 - 1962, France), Henri Matisse (1869 - 1954, France), François Morellet (1926 - 2016, France), Takashi Murakami (1962, Japan), Philippe Parreno (1964, France), Sigmar Polke (1941 - 2010, Germany), Gerhard Richter (1932, Germany), Wilhelm Sasnal (1972, Poland), Kiki Smith (1954, USA), Adrián Villar Rojas (1980, Argentina), Anicka Yi (1971, South KoreaIn Tune With The World» Artists include: Some 29 French and international artists presented in two complementary sequences, with works by: Giovanni Anselmo (1934, Italy), Matthew Barney (1967, USA), Christian Boltanski (1944, France), Mark Bradford (1961, USA), James Lee Byars (1932 - 1997, USA), Maurizio Cattelan (1960, Italy), Ian Cheng (1984, USA), Trisha Donnelly (1974, USA), Dan Flavin (1933 - 1996, USA), Cyprien Gaillard (1980, France), Alberto Giacometti (1901 - 1966, Switzerland), Dominique Gonzalez - Foerster (1965, France), Jacqueline Humphries (1960, USA), Pierre Huyghe (1962, France), Yves Klein (1928 - 1962, France), Henri Matisse (1869 - 1954, France), François Morellet (1926 - 2016, France), Takashi Murakami (1962, Japan), Philippe Parreno (1964, France), Sigmar Polke (1941 - 2010, Germany), Gerhard Richter (1932, Germany), Wilhelm Sasnal (1972, Poland), Kiki Smith (1954, USA), Adrián Villar Rojas (1980, Argentina), Anicka Yi (1971, South Koreain two complementary sequences, with works by: Giovanni Anselmo (1934, Italy), Matthew Barney (1967, USA), Christian Boltanski (1944, France), Mark Bradford (1961, USA), James Lee Byars (1932 - 1997, USA), Maurizio Cattelan (1960, Italy), Ian Cheng (1984, USA), Trisha Donnelly (1974, USA), Dan Flavin (1933 - 1996, USA), Cyprien Gaillard (1980, France), Alberto Giacometti (1901 - 1966, Switzerland), Dominique Gonzalez - Foerster (1965, France), Jacqueline Humphries (1960, USA), Pierre Huyghe (1962, France), Yves Klein (1928 - 1962, France), Henri Matisse (1869 - 1954, France), François Morellet (1926 - 2016, France), Takashi Murakami (1962, Japan), Philippe Parreno (1964, France), Sigmar Polke (1941 - 2010, Germany), Gerhard Richter (1932, Germany), Wilhelm Sasnal (1972, Poland), Kiki Smith (1954, USA), Adrián Villar Rojas (1980, Argentina), Anicka Yi (1971, South Korea).