All seven were located in or near
complement genes (that's «
complement» as in the innate immune system complex), which had been implicated in AMD by sequencing
studies over the
past couple of years.
The finding
complements a
study published in Science last month that found some of Greenland's glaciers have doubled in speed over the
past five years, said Jay Zwally, a glaciologist at NASA's Goddard Space Flight Center in Greenbelt, Maryland.
Our findings add insight into the pathways linking early childhood adversity to poor adult wellbeing.29
Complementing past work that focused on physical health, 9 our findings provide information about links between ACEs and early childhood outcomes at the intersection of learning, behavior, and health.29 We found that ACEs experienced in early childhood were associated with poor foundational skills, such as language and literacy, that predispose individuals to low educational attainment and adult literacy, both of which are related to poor health.23, 30 — 33 Attention problems, social problems, and aggression were also associated with ACEs and also have the potential to interfere with children's educational experience given known associations between self - regulatory behavior and academic achievement.34, 35 Consistent with the original ACE
study and subsequent research, we found that exposure to more ACEs was associated with more adverse outcomes, suggesting a dose — response association.3 — 8 In fact, experiencing ≥ 3 ACEs was associated with below - average performance or problems in every outcome examined.