Sentences with phrase «complex brain connectivity»

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The emergence of a large brain, with complex connectivity among neurons, suggests that the brain itself is an organ of adaptability.
In humans, the cerebellum's extensive connectivity with the rest of the brain suggests it does far more than learn motor skills: it has been shown to have a part in both perception and cognition, with recent work linking cerebellar dysfunction to such complex diseases as schizophrenia and autism.
«As far as we know, this is one of the first studies of dyslexia to examine differences in functional connectivity across the whole brain, shedding light on the brain networks that crucially support the complex task of reading,» added Finn.
More recently, I have demonstrated the feasibility of using fMRI in combination with pharmaco - genetic silencing to dissect the circuital basis of complex behaviors, and demonstrated for the first time that the mouse brain contains distributed resting - state functional connectivity networks, including plausible homologues of the human default - mode (DMN) and salience networks.
My main goals are: a) to unravel the functional and anatomical connectivity of the primate prefrontal cortex circuitry within the framework of complex cognitive tasks, b) to generate tools and techniques that allow manipulating prefrontal cortex function and therefore generate symptoms of mental disorders in behaving non-human primates, and c) to produce interventions (e.g., deep brain stimulation or local / systemic drug delivery) that allow rescuing the generated disease phenotypes.
Theoretical and empirical work is beginning to reveal that autism is associated with a complex functional phenotype characterized by both hypo - and hyper - connectivity of large - scale brain systems.
Relationships between functional and structural connectivity are complex, even in the neurotypical adult brain (Damoiseaux and Greicius, 2009), and these relationships undergo significant changes with development (Supekar et al., 2010; Uddin et al., 2011).
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